Ultrastructure of rat ovarian interstitial cells I. Normal structure and regressive changes following hypophysectomy

Ultrastructural features of ovarian interstitial tissue in a wild mouse, Apodemus flavicollis, at various reproductive stages, with a note on its histochemistry at the onset of the breeding period

“…Such studies all agree that the ultrastructure of interstitial cells is one characteristic of steroid-producing cells and is composed of mitochondria with tubular cristae, lipid droplets and smooth endoplasmic reticulum, as reported, for example, in the rabbit (Davis and Broadus 1968), cat (Nesci and Motta 1969), mouse, cat, and rabbit (Motta et al 1971), and rat (Carithers and Green 1972a;Al-Mehdi 1979).…”

“…An extended appearance of the vesicles of smooth endoplasmic reticulum has been reported, for example, in the interstitial cells of adult human ovary (Motta 1972), in those of the rat (Carithers and Green 1972a), and in those of the cat (Nesci and Motta 1969;Motta et al 1972). This was observed in A.jlavicollis, but only in specimens in which perfusion fixation of the ovaries had been inadequate.…”

“…Moreover, the Golgi complex is reduced in size and in the number of its associated vesicles (Flerko et al 1967;Carithers and Green 1972a;Capps et al 1978) Hypophysectomy causes similar ultrastructural modifications of interstitial cells in the rabbit (Davies and Broadus 1968). During the nonbreeding period and during pregnancy, ovarian interstitial cells of the A. jlavicollis ultrastructurally resembled those of the hypophysectomized rat and rabbit; thus, it may be concluded that stimulation of interstitial tissue is low in the A. jlavicollis during those periods.…”

Comparative morphological and histochemical observations on the ovarian stromal compartment in mammals with special reference to steroidogenesis

“…'flic diffuse lipoproteins of liistochemical studies presum ably derive from the abundantly developed agranular endo plasmic reticulum of steroid gland cells including the present inter stitial gland cells of thecal and strom al origin [Muta, 1958;Motta, 1966;Beltermann and Stegner, 1968;Davies and Broadus, 1968;Motta et «/., 1968;Christensen and Gillim, 1969;F awcett et «/., 1969;Dahl, 1970;Motta and T akeva. 1970;Carithers and Green, 1972a,b|. The ovarian interstitial gland cells are charac on tlie ovarian stromal compartment in mammals .…”

Morphological and morphometric changes in the ovaries of white‐footed mice (Peromyscus leucopus) following exposure to long or short photoperiod

“…LP induced hypertrophy and maturation of the interstitial gland cells, while SP caused atrophy of these cells. The structure of the interstitial gland cells after SP reminds one of the so-called "deficiency-cells" in the rat ovary; they appear in the interstitial cortical tissue of senile rats or after hypophysectomy of fertile rats and can be stimulated to full size by exogenous LH (Carithers and Green, 1972;Crumeyrolle-Arias et al, 1976). In this context it is of interest that in the dog ovary the mature cell type can be provoked and its number increased after a 1200 R whole-body x-irradiation (Spanel-Borowski and Calvo, 1982).…”