Ultrastructural Changes With Age in the Human Superior Laryngeal Nerve

Age‐Related Changes in Human Laryngeal Nerves

“…The results of this research showed that the SLN had an intraperineurial area larger than that of the RLN, with a statistically significant difference (Table 1). The SLN had a mean area of 0.44 mm 2 on both sides, consistent with the mean values published by other authors 6,17 . The RLN had a mean area of 0.21 mm 2 on the right side and 0.23 mm 2 on the left side; a result slightly larger the one in Germain et al, 17 probably due to the fact that the section level performed in this research was 1 cm more proximal to the vagus nerve.…”

Myelinated Axons in the Auricular Branch of the Human Vagus Nerve

“…Bodies with a history of diabetes showed lower numbers of thick myelinated axons. This suggests that diabetes could lower the number of myelinated axons in addition to chronic alcoholism and aging, in line with the literature (Guo et al, ; Mortelliti et al, ; Tiago et al, ). However, no reduction in axon number was noted in body #8 with a history of alcoholism.…”

Análise quantitativa das fibras mielínicas dos nervos laríngeos em humanos de acordo com a idade

“…34 Ravits et al 45 described a control group (mean age 60.7 years) that had a mean density of 9,420 fiber/mm 2 in the RLN, which is lower than our values, but which may be related to a decrease in smaller diameter myelin fibers as a result of predisposing factors associated with malignancies, such as alcoholism or the paraneoplastic syndrome. Other authors have studied SLN fiber density per mm 2 in normal subjects, 18 having reached similar results to those in the current study, that is, a mean density of about 20,000 myelin fibers per mm 2 .…”

“…The mean area of the SLN in both sides was 0.44 mm 2 , which is similar to published mean values. 18,34 The mean area of the RLN was 0.21mm 2 on the right and 0.23mm 2 on the left, which is slightly higher than the results published by Germain et al 34 , probably due the fact that we sectioned the nerve 1cm more proximal to the vagus nerve. Repice 47 reported that the cross-sectional are of the RLN was larger than that of the SLN, which runs contrary to our results and to other published data.…”