Ultrastructural and Immunofluorescence Studies of Placental Tissue in Hypertensive Diseases of Pregnancy

Chronic anaemia causes degenerative changes in trophoblast cells of the rat placenta

“…Similar degenerative changes in these cells have been reported in hypoxia, [17,18] pre-eclampsia [19] and hypertensive disease of pregnancy. [20] The changes are concordant with reports that these cells are sensitive to factors which cause placental injury. [13,21,22] Many of them, especially those related to hypoxia occur due to placental apoptosis consequent to oxidative stress.…”