“…With the introduction of lymphatico-venous anastomosis (LVA) in the 1960s, 1 it shed lights on surgical treatments for lymphedema. Supermicrosurgical LVA was first reported and popularized by Koshima et al [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] LVA can improve lymphedema by channeling lymphatic fluid from lymphatic collecting vessels (LCVs) into vein, thereby reducing accumulated lymph in the affected limb. However, pathological changes to LCVs can occur due to factors such as genetics, 21 aging, 22 soft tissue inflammation, 23 trauma, lymph node dissection, tumor resection, 21,24 and irradiation, 21,25 which can all lead to lymphedema.…”