Ultrasound tagged light imaging in turbid media in a reflectance geometry

Abstract

A combination of light and focused ultrasound waves provides a unique way to obtain directly three-dimensional absorption data in a turbid medium. We present the combination of an ultrasound wave and light in which both the input and the output optodes are on the same side of the sample (reflectance geometry). This technique permits local detection in depth of the presence of a purely absorbing object, without further mathematical processing. It is a promising technique for medical imaging and monitoring of tissues.

Mechanisms of Ultrasonic Modulation of Multiply Scattered Coherent Light: An Analytic Model

“…In addition, by combining the parallel-detection and the frequency-swept techniques, Yao et al obtained two-dimensional images of biological tissues, in which one of the dimensions was along the acoustic axis [7]. In place of transmission configurations, Lev et al developed a reflection configuration for ultrasoundmodulated optical tomography [8].…”

Acousto-optic effect in random media

“…Two forms of acousto-optic imaging are usually distinguished. Direct imaging employs a focused ultrasound beam for image formation [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. The image is created by scanning the focus of the beam and recording the intensity of the scattered light at a fixed detector.…”

Correlation Transfer and Diffusion of Ultrasound-Modulated Multiply Scattered Light

“…At present, the development of effective detection systems is the subject of intense research. [3][4][5][6][7][8][9][10] Also, the exact nature of the ultrasound-modulation of light in a highly optically scattering medium is still not totally understood due to the complicated light-ultrasound interaction in the presence of optical scatterers. Similarly to dynamic light scattering by scatterers undergoing Brownian motion, 11 dynamic scattering by optical scatterers oscillating in an ultrasound field causes optical frequency shifts.…”