Ultrasound Strain Imaging to Assess the Biceps Brachii Muscle in Chronic Poststroke Spasticity

Gao, Jing; Chen, Johnson; O’Dell, Michael W.; Li, Pai‐Chi; He, Wen; Du, Lijuan; Rubin, Jonathan M.; Weitzel, William F.; Min, Robert J.

doi:10.1002/jum.14558

Cited by 13 publications

(18 citation statements)

References 35 publications

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“…The SR is high in softer or more elastic tissue, whereas it is low in a stiffer or less elastic tissue. As reported, the peak axial SR and peak longitudinal SR of the BBM in healthy adults (40–60 years) were 3.2 ± 0.02 and 4.7 ± 0.08, respectively . However, the SR may vary with aging, between athletes and nonathletes, and between men and women.…”

Section: Methodsmentioning

confidence: 64%

“…Muscle axial and longitudinal peak strain values were estimated by using commercial 2‐dimensional speckle‐tracking software (EchoInsight; Epsilon Imaging, Ann Arbor, MI). To provide the estimated muscle strain to be clinically useful for assessing muscle mechanical properties, we used the reference subcutaneous tissue strain to normalize muscle strain because the force used for manual compression and joint (elbow and ankle) movement in USE is not known . We estimated the peak strain of the muscle.…”

Section: Methodsmentioning

confidence: 99%

“…We developed a strain ratio (SR), which is defined as the muscle peak strain divided by the reference subcutaneous tissue peak strain, to assess the maximum deformation and dynamic displacement of the muscle. Importantly, the strain in the subcutaneous tissue produced by manual compression and joint movement is constant (0.07 ± 0.02) and can be used as a reference to normalize muscle strain in muscle USE . The SR is high in softer or more elastic tissue, whereas it is low in a stiffer or less elastic tissue.…”

Section: Methodsmentioning

confidence: 99%

“…To provide the estimated muscle strain to be clinically useful for assessing muscle mechanical properties, we used the reference subcutaneous tissue strain to normalize muscle strain because the force used for manual compression and joint (elbow and ankle) movement in USE is not known. 13,14 We estimated the peak strain of the muscle. The axial peak strain represents the maximum deformation of the muscle in the axial direction, which is parallel to the direction of the sound beam emitted from the transducer.…”

Section: Muscle Usementioning

confidence: 99%

“…However, all aforementioned techniques are either nonquantitative or are limited to observing the muscle dynamic displacement in real time. Two‐dimensional speckle‐tracking–based ultrasound strain elastography (USE) has proven to be feasible for assessing skeletal muscle mechanical behavior associated with neuromuscular disorders, such as Parkinson disease and poststroke spasticity . In this prospective study, we aimed to assess the feasibility of quantitative ultrasound imaging (QUI) parameters (muscle pixel intensity in grayscale images and muscle strain in USE) in the evaluation of the echogenicity and mechanical behavior of the muscle in adult MS.…”

mentioning

confidence: 99%

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Quantitative Ultrasound Imaging to Assess Skeletal Muscles in Adults with Multiple Sclerosis: A Feasibility Study

Gao

Memmott

Poulson

et al. 2019

J of Ultrasound Medicine

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Objectives The aim of this study was to assess the feasibility of quantitative ultrasound imaging (QUI) in assessing the biceps brachii muscle and gastrocnemius muscle in adults with multiple sclerosis (MS). Methods From May to October 2018, we prospectively performed B‐mode ultrasound imaging and ultrasound strain elastography of the biceps brachii muscle and gastrocnemius muscle in 24 patients with MS and 10 age‐matched healthy volunteers. ImageJ (https://imagej.nih.gov/ij) was used to assess the muscle pixel intensity in grayscale images. Using 2‐dimensional speckle‐tracking software, we estimated the muscle axial peak strain (maximum deformation) produced by manual compression with an ultrasound transducer and the muscle longitudinal peak strain (maximum displacement) produced by passive elbow and ankle movements. Muscle QUI parameters used in the study included the mean pixel intensity, axial peak strain ratio (SR = muscle strain/subcutaneous tissue strain), and longitudinal peak SR. Statistical analyses included 1‐way analysis of variance and a post hoc test to examine the differences in QUI parameters among 3 groups (1, affected muscle in patients with MS; 2, unaffected muscle in patients with MS; and 3, healthy muscle in controls) and, in all paired groups, an unpaired t test to compare the muscle SR in patients with MS with a Modified Ashworth Scale (MAS) score of 1 or higher to those with an MAS score of 0. Results The mean age of the 24 patients with MS was 43 years, and all patients and volunteers were female. We observed a significant difference in QUI parameters among the affected muscle in MS, unaffected muscle in MS, and healthy muscle in all paired groups and in patients with MS between an MAS score of 1 or higher and an MAS score of 0 (all P < .05). Interobserver and intraobserver variability in performing QUI was good (intraclass correlation coefficients >0.75). Conclusions Our results suggest that QUI is feasible to assess muscle echogenicity and mechanical behaviors in adult MS.

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Section: Methodsmentioning

confidence: 64%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Muscle Usementioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Quantitative Ultrasound Imaging to Assess Skeletal Muscles in Adults with Multiple Sclerosis: A Feasibility Study

Gao

Memmott

Poulson

et al. 2019

J of Ultrasound Medicine

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Spasticity evaluation and management tools

Howard

Patel

2023

Muscle and Nerve

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Spasticity is a complex and often disabling symptom for patients with upper motor neuron syndromes. Although spasticity arises from neurological disease, it often cascades into muscle and soft tissue changes, which may exacerbate symptoms and further hamper function. Effective management therefore hinges on early recognition and treatment.To this end, the definition of spasticity has expanded over time to more accurately

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Ultrasound elastography in neuromuscular and movement disorders

et al. 2019

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Ultrasound Strain Imaging to Assess the Biceps Brachii Muscle in Chronic Poststroke Spasticity

Abstract: Ultrasound strain imaging seems to be feasible for characterizing the biceps brachii muscle in chronic poststroke spasticity.

Cited by 13 publications

References 35 publications

Quantitative Ultrasound Imaging to Assess Skeletal Muscles in Adults with Multiple Sclerosis: A Feasibility Study

Quantitative Ultrasound Imaging to Assess Skeletal Muscles in Adults with Multiple Sclerosis: A Feasibility Study

Spasticity evaluation and management tools

Ultrasound elastography in neuromuscular and movement disorders

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