2015
DOI: 10.3109/03009742.2015.1011228
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Ultrasound signs of pulmonary fibrosis in systemic sclerosis as timely indicators for chest computed tomography

Abstract: TUS imaging of pleural/subpleural structures can detect ultrasonographic signs of initial PF prior to the onset of respiratory symptoms and function test abnormalities and, together with current criteria, could thereby enable exclusion of PF in SSc patients. Indicating some patients for selective referral to HRCT can thereby delay unwarranted procedures, provided that pulmonary function and TUS images are stable.

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Cited by 65 publications
(71 citation statements)
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“…Sixty-one patients with diagnosis of IPF secondary to different diseases (idiopathic pulmonary fibrosis, sarcoidosis, hypersensitivity pneumonitis, silicosis, viral pneumonias, and CTDs) were involved in the study. All patients showed bilateral B-lines that correlated Sperandeo et al [15] addressed their study to investigate if the potential of US in detecting pleural abnormalities (thickening, pleural/subpleural nodules, and other subpleural lung abnormalities) could play a key role in the detection of subclinical IPF using HRCT assessment as comparison. They performed chest US and HRCT in 175 SSc patients.…”
Section: Evidence Supporting the Role Of Us In Ipf In Sscmentioning
confidence: 92%
See 1 more Smart Citation
“…Sixty-one patients with diagnosis of IPF secondary to different diseases (idiopathic pulmonary fibrosis, sarcoidosis, hypersensitivity pneumonitis, silicosis, viral pneumonias, and CTDs) were involved in the study. All patients showed bilateral B-lines that correlated Sperandeo et al [15] addressed their study to investigate if the potential of US in detecting pleural abnormalities (thickening, pleural/subpleural nodules, and other subpleural lung abnormalities) could play a key role in the detection of subclinical IPF using HRCT assessment as comparison. They performed chest US and HRCT in 175 SSc patients.…”
Section: Evidence Supporting the Role Of Us In Ipf In Sscmentioning
confidence: 92%
“…Only recently has it been proposed as a valid criterion for the assessment of IPF in patients with autoimmune rheumatic diseases [13][14][15][16][17] compared with HRCT as the concurrent "gold standard." This has opened new research fields in US focused on its use for the assessment of IPF in systemic sclerosis (SSc) and other autoimmune rheumatic disorders.…”
Section: Introductionmentioning
confidence: 99%
“…Well‐established fibrosis results in a B7 pattern, while early stages of ILD leads to a B3 pattern due to involvement of the alveolar wall caused by inflammatory cells and edema . Other ultrasonographic signs of ILD are an irregular and thickened pleural line and pleural/subpleural nodules …”
Section: Differential Diagnosis Of B Linesmentioning
confidence: 99%
“…Nonetheless, if positive, TUS could hasten the prescription of more efficient imaging (CT or NMR); and (4) pleural line thickening. This is a minor but relevant clue, detected in several diffuse pulmonary interstitial disease[41] and in conditions such as asbestosis[21,42,43]. This can be an early sign of involvement or of worsening of an already known disease, and can help in the decisional tree for the prescription of a radiological examination - CT.…”
Section: The Procedure: Needs Facilities Collaboration and Indicationsmentioning
confidence: 99%