2015
DOI: 10.1002/uog.14915
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Ultrasound screening for fetal growth restriction at 36vs32 weeks' gestation: a randomized trial (ROUTE)

Abstract: Objective To compare the utility of routine thirdtrimester ultrasound examination at 36 weeks' gestation with that at 32 weeks in detecting fetal growth restriction (FGR). Methods (odds ratio (OR), 3.4 (95% CI,.7)), neonatal admission (OR, 2.23 (95% CI,), hypoglycemia (OR, 9.5 (95% CI,) and hyperbilirubinemia (OR, 9.0 (95% CI,

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Cited by 96 publications
(88 citation statements)
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“…fetal weight or other biometric parameters estimated to be over the 10th percentile or measures <10th percentile, but not noted or considered important). Our findings of low suspicion are concordant with other studies using our definition of suspicion of FGR as well as those using more detailed variables . Finally, about 15% of data were missing in our models, but models using multiple imputation provided very similar results.…”
Section: Commentsupporting
confidence: 90%
“…fetal weight or other biometric parameters estimated to be over the 10th percentile or measures <10th percentile, but not noted or considered important). Our findings of low suspicion are concordant with other studies using our definition of suspicion of FGR as well as those using more detailed variables . Finally, about 15% of data were missing in our models, but models using multiple imputation provided very similar results.…”
Section: Commentsupporting
confidence: 90%
“…Given these contradictory hypotheses, more research on the usefulness and accuracy of a routine third‐trimester ultrasonography in low‐risk pregnancies is warranted. In accordance with recent data suggesting that the detection of fetal growth restriction was superior at 36 weeks of pregnancy compared with 32 weeks, the present study assessed the intra‐ and inter‐observer reproducibility of biometric measurements at 35 +0 to 36 +6 weeks of pregnancy. Moreover, there is also controversy regarding the accuracy of ultrasonography fetal weight estimates in the third trimester in patients with high BMI in comparison with those with lower BMI; in the present study, the reproducibility of ultrasonography parameters was assessed among patients of different BMI groups in an attempt to validate third‐trimester ultrasonography assessment in this population.…”
Section: Discussionmentioning
confidence: 57%
“…These findings have implications with regard to whether routine third-trimester sonographic surveillance in women with uncomplicated pregnancies may or may not be clinically beneficial (23,24). Our results suggest that women with uncomplicated pregnancies experience fetal growth aberration which is associated with increased severe neonatal morbidity.…”
Section: Discussionmentioning
confidence: 99%