Ultrasound score combined with liver stiffness measurement by sound touch elastography for staging liver fibrosis in patients with chronic hepatitis B: a clinical prospective study

Huang, Kun; Li, Qinyuan; Zeng, Weiliang; Chen, Xin; Liu, Li; Wan, Xiang; Feng, Cheng; Li, Zhiyan; Liu, Zhong; Dong, Changfeng

doi:10.21037/atm-22-505

Cited by 3 publications

(1 citation statement)

References 37 publications

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“…Ultrasonography is a more practical choice for initial diagnostic and follow-up exams since it is a safe, non-invasive, and affordable procedure that does not require sedation or anesthesia [16,17]. The ultrasound study protocol includes a serial imaging of liver lobes to assess certain criteria such as parenchymal echotexture, focal lesions, volumetric changes, and edge evaluation [18,19]. Following fibrosis occurrence in some parts of the liver, there are changes in ultrasound properties (absorption and reflection) [20,21].…”

Section: Introductionmentioning

confidence: 99%

Ultrasonographic Evaluation of Liver Tissue after Surgically Induced Bile Duct Ligation in Dogs

Shekho,

Ali,

Al-Iraqi

2024

Egyptian Journal of Veterinary Sciences

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HE current study used ultrasound to assess the induced hepatic fibrosis by ligation of common bile duct using surgical stainless-steel wire in 18 healthy local adult dogs of both sexes, weighing (20±5) kgs and aged (24±6) months. All animals were subjected to evaluated the progression of hepatic fibrosis by clinical and ultrasound examinations using a transabdominal convex transducer at frequency (5 MHz) to diagnose developing of surgically induced hepatic fibrosis at 0, 7, 14 and 21 days, respectively, after ligation of the common bile duct. Clinical results such as severe abdominal pain, anorexia, emaciation, jaundice and pale of mucus membrane were observed. Ultrasonographical examination of liver revealed dilatation of the gallbladder, common bile duct and portal vein as well as increased in thickness and echogenicity of liver tissue starting from the 7 th day post-ligation till reaching the maximum in the 21 days. There was a significant difference in echogenicity of liver parenchyma between groups during the 0,7,14 and 21 days of the experiment in all dogs p<0.01. In conclusion, the use of ultrasound imaging to diagnose, evaluate and follow-up the diffused liver disease models is feasible and beneficial value to monitor the development of levels and stages of hepatic fibrosis and cirrhosis of individual dogs.

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Section: Introductionmentioning

confidence: 99%

Ultrasonographic Evaluation of Liver Tissue after Surgically Induced Bile Duct Ligation in Dogs

Shekho,

Ali,

Al-Iraqi

2024

Egyptian Journal of Veterinary Sciences

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The role of sound touch elastography in assessment of liver fibrosis in chronic liver disease keeping APRI as the reference standard

Sushaal,

Patil,

Patil

2023

Abdom Radiol

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Linear Combination of Leukocyte Count and D-Dimer Levels in the Diagnosis of Patients with Non-traumatic Acute Abdomen

Zararsız¹

2023

Medical Records

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Aim: Rapid intervention is required in patients with non-traumatic acute abdominal pain. It is very important to distinguish between surgical and non-surgical pathologies during this intervention. This study aimed to increase the diagnostic accuracy by combining the leukocyte count and D-dimer levels used in this evaluation with linear combination methods. Material and Method: Logistic regression, scoring, min-max, minimax, Su & Liu, Pepe & Thompson, Pepe, Cai & Langton, and Todor & Saplacan methods were used as linear combination methods. The data set was divided into 70% training set and 30% test set. Parameter optimization was performed on the training data by 5 fold cross-validation method using 10 repeats. The area under the ROC curve, sensitivity, selectivity, accuracy, positive and negative predictive value, and positive and negative likelihood ratio statistics were used in the performance evaluation. Results: The area under the ROC curve statistic for D-dimer level and log-transformed leukocyte count variable were obtained as 0.71 and 0.70, respectively. The accuracy rate was 0.69 for the D-dimer level and 0.73 for log-transformed leukocyte count. For the linear combination methods, the area under the ROC curve was between 0.77 and 0.81, and the accuracy statistics were between 0.72 and 0.79. The best performance was obtained with the min-max method. Conclusion: In patients with non-traumatic acute abdominal pain, leukocyte count and D-dimer levels can be evaluated together by using linear combination methods in differentiating surgical and non-surgical pathologies. The obtained results showed that the diagnostic performance of the combined results with the min-max procedure was higher than the leukocyte count and D-dimer levels.

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Ultrasound score combined with liver stiffness measurement by sound touch elastography for staging liver fibrosis in patients with chronic hepatitis B: a clinical prospective study

Cited by 3 publications

References 37 publications

Ultrasonographic Evaluation of Liver Tissue after Surgically Induced Bile Duct Ligation in Dogs

Ultrasonographic Evaluation of Liver Tissue after Surgically Induced Bile Duct Ligation in Dogs

The role of sound touch elastography in assessment of liver fibrosis in chronic liver disease keeping APRI as the reference standard

Linear Combination of Leukocyte Count and D-Dimer Levels in the Diagnosis of Patients with Non-traumatic Acute Abdomen

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