Ultrasound prevalence of wrist, hand, ankle and foot synovitis and tenosynovitis in systemic sclerosis, and relationship with disease features and hand disability

Abstract

n'entend donner aucune approbation ni improbation aux opinions émises dans les thèses ; ces opinions sont considérées comme propres à leurs auteurs.

Rheumatoid Hand and Other Hand-deforming Rheumatic Conditions

“…Both US and MRI may demonstrate hypoechoic and hypointense dermal thickening, possibly associated with a fibrous infiltration of the hypodermal tissue. [42][43][44][45][46][47] Elastography of the skin and subdermis has been used more recently, both in adults and children; however, the role of US in this skin assessment is yet to be defined.…”

A comprehensive framework for navigating patient care in systemic sclerosis: A global response to the need for improving the practice of diagnostic and preventive strategies in SSc

“…The presence of tendon friction rubs (TFRs), another source of pain from inflammation and tendon sheath irritation, indicates active cutaneous or inflammatory disease that without appropriate treatment, portends a poor prognosis including worsening skin and risk for SRC [38,62,63]. Thus, careful tendon examination is necessary, and ultrasound can helpful to assess for active joint inflammation and risk for disability [63].…”

The role of ultrasound in systemic sclerosis: On the cutting edge to foster clinical and research advancement

“…11–16 However, the presence of synovitis is significantly underestimated by clinical examination alone compared to US. 11,14–17 In a meta-analysis which included seven studies, the prevalence (95% confidence interval) of radiologically detectable (by plain radiography) and clinical arthritis was reported to be 26% (16.7, 36.1%) and 23% (14.9, 30.9%), respectively. 18 Similarly, inflammatory tendon disease is common in SSc and US is superior to clinical examination in detecting the presence of tenosynovitis.…”

“…4,10 The high prevalence of US synovial involvement is well established in SSc, including foot involvement. [11][12][13][14][15][16] However, the presence of synovitis is significantly underestimated by clinical examination alone compared to US. 11,[14][15][16][17] In a meta-analysis which included seven studies, the prevalence (95% confidence interval) of radiologically detectable (by plain radiography) and clinical arthritis was reported to be 26% (16.7, 36.1%) and 23% (14.9, 30.9%), respectively.…”

“…18 Similarly, inflammatory tendon disease is common in SSc and US is superior to clinical examination in detecting the presence of tenosynovitis. 12,16,19,20 For example, in the study by Chitale et al, 17 which included 17 patients with SSc reporting arthralgia and no overt inflammatory arthritis on clinical examination, the prevalence of tenosynovitis at baseline and 6 months was 46% and 47%, respectively. 17 US has also revealed novel insights into the origin of TFRs in SSc.…”