Ultrasound of regional lymph nodes in the follow-up of malignant melanoma

Blum, Andreas; Carl, Marina; Rassner, G.

doi:10.1097/00008390-199505001-00017

Cited by 10 publications

(3 citation statements)

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“…At the current time, lymph node sonography has an established role in the diagnosis and follow‐up of patients with malignant melanoma. In the hands of an experienced investigator, the method achieves a high sensitivity and specificity 18–20. In our opinion, preoperative imaging of the SLN represents an additional, new indication for lymph node ultrasonography in malignant melanoma.…”

Section: Discussionmentioning

confidence: 90%

Preoperative ultrasonographic identification of the sentinel lymph node in patients with malignant melanoma

Kahle¹,

Hoffend²,

Wacker³

et al. 2003

Cancer

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BACKGROUND Dissection of the “sentinel lymph node” (SLN) as identified by lymphoscintigraphy is becoming increasingly important in the treatment of patients with malignant melanoma. The purpose of the current study was to determine whether the SLN also could be identified by ultrasound. METHODS Sixty‐seven patients with malignant melanoma (40 females and 27 males, with an average age of 48.8 years) in whom extirpation of the SLN was indicated underwent ultrasonography of the regional lymph nodes prior to preoperative lymphoscintigraphy. The location of the melanoma was the legs in 30 patients, the arms in 14 patients, and the trunk in 23 patients. During regional ultrasonography, the location of the lymph nodes that differed in the cortex/medulla ratio from the surrounding lymph nodes was marked on the skin corresponding to the planes of insonation (M1) when the probe was held vertically to the skin surface. After lymphoscintigraphy using technetium‐99m, the position of a gamma probe at which the highest count rate vertical to the skin surface was recorded also was marked (M2). RESULTS In the inguinal region, the agreement between M1 and M2 was found to be 100% (40 of 40 SLNs) and was 72.5% in the axilla (29 of 40 SLNs). In patients with melanomas located on the leg, the location of M1 and M2 agreed in 97% of cases (36 of 37 lymph nodes in 30 patients); in patients with melanomas located on the arms, the agreement was 76% (13 of 17 lymph nodes in 14 patients) and in patients with melanomas located on the trunk, the agreement was 75% (21 of 28 lymph nodes in 23 patients). The position documented by ultrasound relative to the neighboring structures of the SLN was confirmed intraoperatively in all cases. CONCLUSIONS The results of the current study indicate that the SLN in patients with melanoma located on the limbs, especially the legs, are characterized by a specific sonomorphologic pattern. Preoperative sonography might constitute an important addition to lymphoscintigraphy in the planning of SLN biopsy. Cancer 2003;97:1947–54. © 2003 American Cancer Society. DOI 10.1002/cncr.11261

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Section: Discussionmentioning

confidence: 90%

Preoperative ultrasonographic identification of the sentinel lymph node in patients with malignant melanoma

Kahle¹,

Hoffend²,

Wacker³

et al. 2003

Cancer

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“…In der Hand eines erfahrenen Untersuchers erreicht die Methode eine hohe Sensitivität und Spezifität [2,3,8]. In der Hand eines erfahrenen Untersuchers erreicht die Methode eine hohe Sensitivität und Spezifität [2,3,8].…”

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Sonographie des Sentinel-Lymphknotens bei malignem Melanom

et al. 2000

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“…There is very little in the literature in pediatric or adult medicine about the accuracy of physical examination for the detection of hepatosplenomegaly. However, comparing physical accuracy to medical imaging tests has been examined for other issues [8][9][10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

Accuracy of physical examination versus ultrasound in the detection of hepatosplenomegaly at diagnosis of pediatric leukemia

Cyr¹,

Johnston

2013

J Hemat Malig

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Background: Hepatosplenomegaly (HSM) is common at diagnosis of pediatric leukemia and is diagnosed through palpation or ultrasound. We sought to determine if ultrasound was necessary.Methods: Spleen and liver size was recorded from palpation and ultrasound for 94 children with a new diagnosis of leukemia.Results: Palpation was correct in detecting 71% (173/245) of cases of splenomegaly and 68% (172/254) of cases of hepatomegaly. There was no relationship between body mass index and clinician accuracy at diagnosis of HSM. Ultrasound examination had abnormal findings excluding HSM in 56% of patients. Conclusions:Ultrasound examination is a warranted investigation for newly diagnosed children with leukemia.

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Ultrasound of regional lymph nodes in the follow-up of malignant melanoma

Cited by 10 publications

References 0 publications

Preoperative ultrasonographic identification of the sentinel lymph node in patients with malignant melanoma

Preoperative ultrasonographic identification of the sentinel lymph node in patients with malignant melanoma

Sonographie des Sentinel-Lymphknotens bei malignem Melanom

Accuracy of physical examination versus ultrasound in the detection of hepatosplenomegaly at diagnosis of pediatric leukemia

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