Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics

Kuroki, Hiroshi; Nakagawa, Yasuaki; Mori, Koji; Kobayashi, Masahiko; Yasura, Ko; Okamoto, Yukihiro; Suzuki, Takashi; Nishitani, Kohei; Nakamura, Takashi

doi:10.1186/ar2727

Cited by 4 publications

(2 citation statements)

References 7 publications

(6 reference statements)

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“…For implanted constructs, non-invasive methods such as MRI [631][632][633][634] and ultrasound [635][636][637] can be applied. Stains such as alcian blue, safranin O (often used together with fast green), and sirius red are regularly employed, along with combinations such as Movat's pentachrome and hematoxylin/eosin to histologically demonstrate the location of glycosaminoglycan, collagen, and other ECM.…”

Section: Assessment and Design Standards For Tissue Engineeringmentioning

confidence: 99%

Articular Cartilage Tissue Engineering

Athanasiou¹,

Darling²,

Hu³

2009

Synthesis Lectures on Tissue Engineering

184

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Section: Assessment and Design Standards For Tissue Engineeringmentioning

confidence: 99%

Articular Cartilage Tissue Engineering

Athanasiou¹,

Darling²,

Hu³

2009

Synthesis Lectures on Tissue Engineering

184

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“…Therefore, cartilage thickness cannot become a single index for evaluating cartilage degeneration. The quantification of the elastic properties of distal FAC is essential for gaining insight into the degeneration of articular cartilage [ 11 ]. Early detection of KOA is needed to delay the progression and minimize cartilage degeneration.…”

Section: Introductionmentioning

confidence: 99%

Quantifying Region-Specific Elastic Properties of Distal Femoral Articular Cartilage: A Shear-Wave Elastography Study

Deng

Lin

et al. 2022

Applied Bionics and Biomechanics

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Knee osteoarthritis is a disease with the degeneration of articular cartilage as its main feature. Cartilage thickness cannot become a single index to evaluate cartilage degeneration, so it is essential to also evaluate the stiffness. The purposes were as follows: (1) to examine test-retest reliabilities of the elastic modulus measurement in distal femoral articular cartilage (FAC) and compare the changes in specific-regional of distal FAC, (2) to explore the difference in distal FAC stiffness and thickness between the dominant and nondominant sides, and (3) to examine the correlation between the elastic properties of cartilage and the thickness of cartilage. Twenty healthy participants were recruited. The stiffness of distal FAC at the lateral femoral condyle (LFC), medial femoral condyle (MFC), and intercondylar notch (IN) was quantified using shear-wave elastography (SWE). Intra- and interrater reliabilities were excellent for measuring the stiffness of distal FAC (ICC: 0.83-0.98). About a 50% increase in the stiffness of LFC (40.78 kPa) was found when compared with IN (21.82 kPa) and MFC (18.34 kPa). No significant difference was found between the dominant and nondominant sides in distal FAC stiffness and thickness. There was no correlation between the stiffness and thickness of the distal FAC. In conclusion, SWE can quantify the stiffness of the distal FAC.

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Articular Cartilage Tissue Engineering

Athanasiou

Darling

2010

Synthesis Lectures on Tissue Engineering

View full text Add to dashboard Cite

Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics

Cited by 4 publications

References 7 publications

Articular Cartilage Tissue Engineering

Articular Cartilage Tissue Engineering

Quantifying Region-Specific Elastic Properties of Distal Femoral Articular Cartilage: A Shear-Wave Elastography Study

Articular Cartilage Tissue Engineering

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