Ultrasound-guided percutaneous microwave ablation for symptomatic uterine fibroid treatment – A clinical study

Abstract

PMTA for fibroid is feasible and safe, and it is an easy and fast procedure that is minimally invasive.

Feasibility study on energy prediction of microwave ablation upon uterine adenomyosis and leiomyomas by MRI

“…As one of the minimally invasive therapies, PMWA is an easy and fast procedure with the advantage of security, effectiveness and reliability. 11 In the course of PMWA, the number of antennas and their placement depend on the ablation zones obtained from ex vivo porcine musculature models. So far, there is no quantitative clinical study about ablation zones of PMWA of uterine leiomyomas or adenomyosis.…”

“…The output energy of the MW was set at 50 W. A single antenna was used for leiomyomas with mean diameters ,5 cm; double antennas were used with mean diameters .5 cm, which were inserted at a distance of 1 cm in leiomyomas. 11 Generally, two antennas were used for adenomyosis when the lesions were .5 cm thick. For large lesions with mean diameters .5 cm, the ablation was first performed using two antennas with 50 W for 300 s, and the antennas was then withdrawn along the long axis or re-inserted into the unablated zone for another ablation session.…”

“…However, medical technology advancements have made less invasive treatment options available, such as uterine artery embolization (UAE), [4][5][6] high-intensity focused ultrasound (HIFU), [7][8][9] radiofrequency (RF) 10 and percutaneous microwave ablation (PMWA). 11,12 PMWA is a minimally invasive technique for the treatment of uterine leiomyomas and adenomyosis by inducing tissue necrosis through heat. Previous reports 11,12 have indicated that PMWA provides a feasible, safe and reliable alternative for the treatment of uterine leiomyomas and adenomyosis.…”

“…11,12 PMWA is a minimally invasive technique for the treatment of uterine leiomyomas and adenomyosis by inducing tissue necrosis through heat. Previous reports 11,12 have indicated that PMWA provides a feasible, safe and reliable alternative for the treatment of uterine leiomyomas and adenomyosis. However, until now, the energy required per unit volume (EPV) of PMWA in uterine lesions has been unclear, which has limited the widespread use of PMWA therapy.…”

“…During the ablation, variations in the echo from the lesions were monitored by real-time ultrasonography. 11 The MW therapy was stopped when the hyperecho (caused by microbubbles generated during MW emission and representing roughly the ablation zone) covered the entire lesion. Finally, CE ultrasonography was performed to evaluate ablation effects.…”