Ultrasound-guided fine-needle capillary cytology of parotid gland masses coupled with a rapid-on-site evaluation improves results

Barats, R.; Evrard, Solène; Collin, Laetitia; Vergez, S.; Gellee, Stéphane; Courtade-Saïdi, Monique

doi:10.1016/j.morpho.2017.06.003

Cited by 12 publications

(14 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indeed, most of the samples from our institution were collected at the initial patient consultation, during which the clinician performed the FNA without ultrasound-guidance. In fact, we previously showed, as did others, that ultrasound guided FNA increases the quality of the sample collected when compared to FNA performed in the absence of ultrasound guidance [12,13]. This may explain the high frequency of samples with cystic content and without any informative epithelial cells observed, and also why the ROM in the ND category of our study is higher than in the MSRSGC (34% vs. 25%) [3].…”

Section: Discussionsupporting

confidence: 55%

A 4-Year Retrospective Analysis of Salivary Gland Cytopathology Using the Milan System for Reporting Salivary Gland Cytology and Ancillary Studies

Dubucs

Basset

d’Aure³

et al. 2019

Cancers

View full text Add to dashboard Cite

The cytopathology of salivary glands presents major challenges due to the heterogeneity of benign and malignant neoplasms, which is reflected in the large range of WHO 2017 Classifications. Fine needle aspiration (FNA) of salivary gland tumours is still the favoured initial approach as it results in good sensitivity and specificity. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was published in 2018 and comprises seven categories. We report results from a 4-year retrospective analysis of 328 salivary gland FNAs which were reviewed and classified according to the MSRSGC. We assess the risk of neoplasm, the risk of malignancy and the contribution of ancillary studies to the diagnosis. Benign neoplasms were the most frequent diagnosis (44.2%). Malignant and suspicious for malignancy were identified in 11.3% and 4.9% of diagnosed cases, respectively. Histopathological analysis after surgery was available for 216 (65.8%) of the cases. All malignant cases were confirmed post-surgery, and 68.8% of suspicious for malignancy were confirmed as malignant tumours. Immunocytochemistry was informative in 72.3% of cases. Immunocytochemistry and FISH provided the definitive diagnosis in 23.7% and 33% of cases, respectively. In conclusion, the MSRSGC is more effective when specific features of neoplasms can be identified. Ancillary studies help to further characterise salivary gland tumours and thereby increase the accuracy of MSRSGC.

show abstract

Section: Discussionsupporting

confidence: 55%

A 4-Year Retrospective Analysis of Salivary Gland Cytopathology Using the Milan System for Reporting Salivary Gland Cytology and Ancillary Studies

Dubucs

Basset

d’Aure³

et al. 2019

Cancers

View full text Add to dashboard Cite

show abstract

“…In samples-based analysis, two malignancies were originally diagnosed as non-diagnostic, but the diagnostic category increased in repeated FNA. In the literature, ROSE (rapid on site evaluation) also decreased the non-diagnostic rates in salivary gland FNA [34]. According to the Survey on Salivary Gland Cytopathology [3], ROSE is performed by 59% of participants.…”

Section: Discussionmentioning

confidence: 99%

Salivary Gland FNA Diagnostics in a Real-Life Setting: One-Year-Experiences of the Implementation of the Milan System in a Tertiary Care Center

Tommola

Porre

et al. 2019

Cancers

View full text Add to dashboard Cite

The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was introduced in 2018 following other organ specific cytopathological reporting systems and it aimed at bringing a practical, evidence-based, user-friendly classification system with characterization and management algorithms. At the Department of Pathology, Fimlab Laboratories, Tampere, Finland all salivary fine needle aspirations (FNAs) have been given cytopathological diagnoses according to the MSRSGC since January 2018. Analyses of a one-year-period (January 2018–December 2018) consisted of 183 salivary FNA samples from 138 patients with correlation to histopathology in 90 cases with surgical follow-up. The MSRSGC performance in patient based analysis was as follows: accuracy was 90.9%, sensitivity was 61.5%, specificity was 100%, positive predictive value was 100%, and negative predictive value was 89.4%, respectively. Risks of malignancy (ROMs) in MSRSGC categories were: 0.0% (0/15) in non-diagnostic category, 100.0% (1/1) in non-neoplastic category biased by only one falsely-negative lymphoma case, 14.3% (1/7) in atypia of undetermined significance category, 0.0% (0/28) in benign neoplasm category, 27.3% (3/11) in neoplasm of uncertain malignant potential category, and 100% for both suspicious for malignancy (4/4) and malignancy (4/4) categories, respectively. The MSRSGC has been proven as a reliable classification system in salivary gland FNA routine diagnostics in a tertiary care center.

show abstract

“…Barats et al showed in their study that an appropriate specimen must comprise of a minimum six-cell clusters per slide. Unsatisfactory aspirates (insufficient cell number or blood-only aspirates) can occur in up to 18% of cases [70].…”

Section: Fnab and Core Needle Biopsy (Cnb)mentioning

confidence: 99%

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Stoia

Băciuț

Lenghel

et al. 2020

Bosn J of Basic Med Sci

View full text Add to dashboard Cite

An accurate preoperative diagnosis of parotid tumors is essential for selection and planning of the surgical treatment. Various modern cross-sectional imaging and cytologic investigations can support differential diagnosis of parotid tumors. The aim of this study was to achieve a comprehensive and updated review of modern imaging and cytologic investigations used in parotid tumor diagnosis, based on the latest literature data. This literature review could serve as a guide for clinicians in selecting different types of investigations for preoperative differential diagnosis of parotid tumors. Magnetic resonance imaging (MRI) with its dynamic and advanced sequences is the first-line imaging investigation used in differentiating parotid tumors. Computed tomography (CT) and positron emission tomography (PET)-CT provide limited indications in differentiating parotid tumors. Fine needle aspiration biopsy and core needle biopsy can contribute with satisfactory results to cytological diagnosis of parotid tumors. Dynamic MRI with its dynamic contrast-enhanced and diffusion-weighted sequences provides the best accuracy for preoperative differential diagnosis of parotid tumors. CT allows the best evaluation of bone invasion, being useful when MRI cannot be performed, and PET-CT has value in the follow-up of cancer patients. The dual cytological and imaging approach is the safest method for an accurate differential diagnosis of parotid tumors.

show abstract

Ultrasound-guided fine-needle capillary cytology of parotid gland masses coupled with a rapid-on-site evaluation improves results

Cited by 12 publications

References 19 publications

A 4-Year Retrospective Analysis of Salivary Gland Cytopathology Using the Milan System for Reporting Salivary Gland Cytology and Ancillary Studies

A 4-Year Retrospective Analysis of Salivary Gland Cytopathology Using the Milan System for Reporting Salivary Gland Cytology and Ancillary Studies

Salivary Gland FNA Diagnostics in a Real-Life Setting: One-Year-Experiences of the Implementation of the Milan System in a Tertiary Care Center

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Contact Info

Product

Resources

About