Ultrasound-guided fine-needle aspiration cytology of solid pseudopapillary tumor of the pancreas: a tertiary care centre experience

Rao, Ram Nawal; Agarwal, Preeti; Mishra, Deepti; Rai, Praveer; Mitra, Shaila; Bansal, Megha

doi:10.7243/2052-6199-2-2

Cited by 1 publication

(2 citation statements)

References 43 publications

(34 reference statements)

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“…In the present study, we have 8 cases over a period of 2 years. Female preponderance [F: M 7: 1] was observed in the present study in concordance with Martin RC, Klimstra DS et al [3], [7], [8] Female preponderance is probably due to proximity of primordial pancreatic cells to the ovarian ridge during development. [9] SPT can occur in male patients and it has an indolent behaviour.…”

Section: Resultssupporting

confidence: 91%

“…Occasionally, neuron specific enolase and synaptophysin can be positive. [8] Tumour is nonreactive for S-100, CA 19.9 and chromogranin. The main differential diagnosis of SPT includes pancreatic neuroendocrine tumour, acinar cell carcinoma, papillary mucinous carcinoma and intraductal papillary mucinous tumour (IPMT).…”

Section: Sl No Age/sex Presenting Symptoms Location Of the Tumourmentioning

confidence: 99%

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Solid Pseudopapillary Tumour of the Pancreas: A Tertiary Care Centre Experience

Aruna¹,

Mekhala²,

Arasi³

et al. 2016

jebmh

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BACKGROUND Solid pseudopapillary tumour of the pancreas is a rare tumour of low malignant potential occurring predominantly in young females. Its incidence has been increasing due to advanced imaging modalities. As this tumour offers a good prognosis, it is important to make a proper diagnosis to offer better treatment and reduce morbidity. MATERIALS AND METHODS This is a prospective study for a period of 2 years (From May 2014 to April 2016). Of the 52 pancreatic specimens we received after surgery, 9 cases had a prior radiological diagnosis of solid pseudopapillary tumour of the pancreas. The clinical and histopathological characteristics of SPT were studied along with review of literature. Whipple resection specimens which were radiologically diagnosed as adenocarcinoma of the periampullary region were excluded. RESULTS Nine cases were reported radiologically as papillary neoplasm of pancreas. On histopathology, 8 of them were confirmed as solid pseudopapillary tumours of the pancreas. One was a case of serous cystadenoma and other one was pancreatic neuroendocrine tumour. One case which was suspected as pancreatic endocrine tumour radiologically was diagnosed as SPT. CONCLUSION SPT typically is limited to the pancreas at the time of diagnosis, and even with metastasis, an extended complete surgical excision offers good prognosis. Hence, it is important to distinguish it from other tumours of similar morphology. In this study, we discuss the process of establishing the diagnosis accurately of SPN in young patients presenting with pancreatic mass.

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