Ultrasound‐guided Biopsy of the Canine Liver, Kidney, and Prostate

Abstract

Sixty‐nine hepatic, 25 renal, and 16 prostatic biopsies were performed under ultrasound guidance using a biopsy guide. The majority (98 of 110) were tissue‐core biopsies. Multiple attempts at obtaining a sample were required; however, in the kidney, the number of attempts was restricted to two. Adequate samples were obtained in 94% (65/69) hepatic, 88% (22/25) renal, and 94% (5/6) prostatic biopsies. Postbiopsy scanning did not demonstrate parenchymal hemorrhage. In three renal and one prostatic biopsy, gross hematuria, noted immediately following biopsy, resolved in 2–3 days. Animals with prostatic disease frequently had hematuria, making evaluation for this complication difficult. One animal died acutely 2 days following prostatic biopsy due to an unrelated problem, a ruptured aortic àneurysm. Complications were not encountered with the liver biopsy procedure. Animals biopsied under sedation tolerated the procedure well. The authors preferred to anesthetize uncooperative animals and those needing kidney biopsy to minimize the likelihood of complications. Problems encountered during the procedure, overlying bowel gas obscuring the target organ or poor visualization of the biopsy needle, were corrected by changing patient or transducer position or the procedure was postponed. The usefulness of the biopsy procedure is illustrated in four case reports.

Efficacy and Safety of Ultrasound-guided Percutaneous Biopsy of the Right Kidney in Cattle

“…Large blood vessels in the kidney increase the likelihood of hemorrhage after percutaneous renal biopsy [11,19]. Coagulation parameters should be determined before biopsy; however, even with these precautions, complications developed in a study of dogs and cats [1].…”

The Age Dependent Levels of Serum ALP Isoenzymes and the Diagnostic Significance of Corticosteroid-Induced ALP during Long-Term Glucocorticoid Treatment.

“…They were collected by an ultrasound-guided technique described by Hager et al and Hoppe et al [8,13] using an automated biopsy gun (Biopty®, Radiplast, Karlsrogatan 46, 752 39 Uppsala, Sweden) with a 16 gauge 10 cm biopsy Alkaline phosphatase (ALP) is a membrane-associated enzyme present in many tissues; however, only the bone (BALP), liver (LALP) and corticosteroid-induced (CALP) isoenzymes contribute to serum ALP activity in dogs [10]. CALP is present at low levels, but high levels can be induced by abnormal exposure to high concentrations of endogenous or exogenous glucocorticoids [1,3,4,7,11].…”

Clinicopathological changes and effect of imidocarb therapy in dogs experimentally infected with Babesia canis

“…The liver was biopsied under ultrasound guidance on PID 7 in both dogs B SE and C SE , applying an automatic needle biopsy technique (Biopty, Radiplast, Uppsala, Sweden) as described earlier (Hager et al, 1985). Liver biopsy samples were stained with haematoxylin-eosin (HE) and Oil-Red-O for histological analysis.…”