Ultrasound-guided anterior quadratus lumborum block for postoperative pain after laparoscopic pyeloplasty: A randomized controlled trial

Srivastava, Divya; Verma, Reetu; Singh, Tapas Kumar; Verma, Alka; Chandra, Abhilash; Sahu, Sandeep; Mishra, Prabhakar

doi:10.4103/aer.aer_45_20

Cited by 11 publications

(1 citation statement)

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“…Notably, 0.2% levobupivacaine and 0.2–0.5% ropivacaine are the commonly used drug concentrations for peripheral nerve block in clinical anesthesia. Relevant studies have used these concentrations of these local anesthetic solutions to observe the analgesic effect after ESP block [ 9 – 13 ]. Compared with levobupivacaine, ropivacaine is characterized by fewer cardiotoxic effects and a probably greater margin of safety [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of ultrasound-guided erector spinae plane block with dexmedetomidine combined with ropivacaine of the same dose and different concentrations on analgesic effect and rehabilitation quality of patients undergoing thoracoscopic wedge resection of the lung: a prospective, randomized, controlled trial

Jian

Shen

et al. 2022

BMC Anesthesiol

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Objective To investigate the analgesic effect and rehabilitation quality of patients undergoing thoracoscopic wedge resection of the lung under erector spinae plane (ESP) block with dexmedetomidine combined with the same dose and different concentrations of ropivacaine. Methods Seventy patients undergoing thoracoscopic wedge resection were randomly divided into groups A (n = 35) and B (n = 35). To perform ESP block, the groups were administered dexmedetomidine (0.5 μg/kg) combined with 30 mL of 0.33% ropivacaine or 20 mL of 0.5% ropivacaine, respectively, half an hour before general anesthesia induction. We compared the onset time of anesthesia, the block level, and the duration of the block between the two groups. The number of compressions of the analgesic pump within 24 h and 48 h postoperatively and the time of the first compression were noted. The visual analog scale (VAS) scores of static and cough at 0.5 h, 6 h, 12 h, 24 h, and 48 h postoperatively were noted. Furthermore, the 40-item quality of recovery questionnaire (QoR-40) score was recorded at 24 h postoperatively. In addition, we noted the time taken to get out of the bed for the first time, the length of hospital stay, analgesia satisfaction, and the occurrence of related adverse reactions and complications within 48 h postoperatively. Results The range of ESP block was wider in Group A than in Group B (P < 0.05). Group B had a significantly shorter onset time (P < 0.05) and lower static and cough VAS scores at 6 h and 12 h postoperatively (P < 0.05); this was associated with significantly fewer compressions of the analgesic pump within 24 h and 48 h postoperatively and significantly more time until the first compression of the analgesic pump was required (P < 0.05). Group B was associated with significantly superior QoR-40 scores 24 h postoperatively and significantly shorter time to get out of the bed for the first time than Group A (P < 0.05). Conclusion Dexmedetomidine combined with 0.5% ropivacaine for ESP block is better than 0.33% ropivacaine for overall analgesia and postoperative rehabilitation of patients undergoing thoracoscopic wedge resection. Trial registration ChiCTR2200058114, Date of registration: 30/03/2022.

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Section: Discussionmentioning

confidence: 99%