Ultrasound Examination of Hair Follicles in Hidradenitis Suppurativa

Jemec, Gregor B.E.; Gniadecka, Monika

doi:10.1001/archderm.1997.03890440033004

Cited by 52 publications

(38 citation statements)

References 16 publications

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“…Une autre classification proposée par Sartorius [9] (Tableau 2) permet une observation plus dynamique de la sévérité de la maladie. L'intérêt de l'imagerie a été évalué dans la maladie de Verneuil par trois techniques : l'échographie à haute fréquence [10], l'imagerie par résonance magnétique [11] et la fistulographie [12].…”

Section: Discussionunclassified

La maladie de Verneuil : à propos de 107 cas

Belhabib¹,

Krami²,

Errabih³

et al. 2013

Hegel

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RésuméLa maladie de Verneuil est une suppuration chronique fistulisante, sclérosante d'évolution cicatricielle. Son diagnostic est souvent méconnu et confondu avec une autre pathologie suppurative. Cette affection est caractérisée par une évolution longue, un traitement essentiellement chirurgical souvent en plusieurs temps avec un délai de cicatrisation long. C'est une maladie très invalidante au plan social et familial, pouvant entraîner un handicap réel pour le patient. À travers l'analyse de 107 observations de la maladie de Verneuil, nous avons étudié les caractéristiques épidémiologiques et cliniques de cette pathologie. Mots-clés

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Section: Discussionunclassified

La maladie de Verneuil : à propos de 107 cas

Belhabib¹,

Krami²,

Errabih³

et al. 2013

Hegel

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“…Las alteraciones histológicas en la HS demuestran una alteración de la queratinización en la zona infundibular y oclusión, inflamación y necrosis de las glán-dulas sebáceas y/o sudoríparas como fenómeno secundario 5 . Puede haber apocrinitis en un 5% de pacientes 28 .…”

Section: Factores Predisponentes Y Desencadenantesunclassified

“…Pioderma gangrenoso (PG) 28,29 : estudios recientes demuestran una concomitancia clínica de HS y PG en los mismos sitios o en otros diferentes, con ligero predominio en mujeres, con evolución de HS y PG independiente. Las comorbilidades presentes en estos pacientes incluyen acné, artritis, sinovitis, síndrome SAPHO (sinovitis, acné, pustulosis, hiperostosis y osteítis), anemia por deficiencia de hierro, lupus, glomerulonefritis, psoriasis, enfermedad inflamatoria intestinal, enfermedad de Crohn (5%) y enfermedad de Behcet (ocasional).…”

Section: Enfermedades Asociadas a Hidrosadenitis Supurativa 1027 Lasunclassified

“…Las comorbilidades presentes en estos pacientes incluyen acné, artritis, sinovitis, síndrome SAPHO (sinovitis, acné, pustulosis, hiperostosis y osteítis), anemia por deficiencia de hierro, lupus, glomerulonefritis, psoriasis, enfermedad inflamatoria intestinal, enfermedad de Crohn (5%) y enfermedad de Behcet (ocasional). Hallazgos frecuentes en este grupo son la obesidad, la diabetes mellitus de tipo 2 y la enfermedad arterial coronaria 28 . Se plantea que, tanto la HS como el PG, se deberían a una alteración en la regulación, quimiotaxis, fagocitosis y producción de linfocinas 29 .…”

Section: Enfermedades Asociadas a Hidrosadenitis Supurativa 1027 Lasunclassified

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Hidrosadenitis supurativa y procesos afines

Herane¹,

Cabrera²

2012

Más Dermatol.

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RESUMENLa hidrosadenitis supurativa (acné inverso, enfermedad de Verneuil, apocrinitis) es una enfermedad crónica que afecta principalmente a zonas intertriginosas, con nódu-los inflamatorios subcutáneos recurrentes, sinus y cicatrices defectuosas. Se considera una enfermedad de oclusión folicular. Las terapias tradicionales consisten en intervenciones quirúrgicas parciales o extensas, antiandrógenos, antibióticos, inhibidores del factor de necrosis tumoral α, terapia fotodinámica y otras.Palabras clave: hidrosadenitis supurativa, acné inverso, enfermedad de Verneuil. ABSTRACTHidradenitis suppurativa (acne inversa, Verneuil disease, apocrinitis) is a chronic disease primarily affecting intertriginous areas with tender subcutaneous nodules, sinus tracts and abnormal scarring. It is considered a disease of follicular occlusion. Traditional therapies consisting of partial and extensive surgery, antiandrogens, antibiotics, tumour necrosis factor inhibitors, photodynamic therapy are available among others.

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“…Other biochemical markers have been explored in smaller studies, i.e., interleukin (IL)-6, IL-17, sIL2-R, lipocalin-2, miRNAs, complement, chitinase-3-like protein, and S100A8/A9 [9-16]. On the other hand, high-resolution ultrasonography can identify the true extent of lesions in HS, which may be of use both in the preoperative planning and in clinical follow-up of medical treatment [17-21]. The method, however, is not only operator dependent but requires time if full use of it is made.…”

Section: Introductionmentioning

confidence: 99%

Long-Wave Medical Infrared Thermography: A Clinical Biomarker of Inflammation in Hidradenitis Suppurativa/Acne Inversa

Zouboulis¹,

Costa²,

Jemec³

et al. 2019

Dermatology

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Background: A more reliable classification of skin inflammation and severity of active disease results from ultrasound sonography and the new hidradenitis suppurativa/acne inversa (HS) classification system IHS4. However, an objective assessment of skin inflammation in a continuous mode is still the ultimate goal. Long-wave medical infrared thermography (MIT) may offer a blood flow and temperature differential assessment in inflammatory conditions. Objective: To evaluate the application of MIT in HS. Methods: Standardized photography of the areas involved or been candidates for HS involvement was performed and MIT pictures were taken simultaneously and superimposed on the photographs of 18 patients (11 female, 7 male, median age 38.75 years [95% confidence interval 28.5 and 51 years], Hurley score I 5.6%, Hurley score II 38.9%, and Hurley score III 55.5%). A modification of the Otsu’s method facilitated the automatic lesion segmentation from the background, depicting the inflammation area. Moreover, MIT was administered in real-time mode during radical HS surgery. Results: A 1°C temperature difference from a corresponding symmetric body region was indicative of inflammation. MIT figures detected a gradual increase of skin temperature from 33.0°C in healthy skin on average to 35.0–36.6°C at the center of inflamma tory lesions in the axilla and to 35.4–36.9°C at the center of inflammation in the groin area. Real-time MIT assessment enabled the definition of the margins and depth of the surgical intervention during the procedure. Conclusion: MIT is a promising tool for the detection of inflammation severity in HS lesions and can be used as a clinical biomarker in evaluation studies of medical and surgical HS treatment.

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Ultrasound Examination of Hair Follicles in Hidradenitis Suppurativa

Cited by 52 publications

References 16 publications

La maladie de Verneuil : à propos de 107 cas

La maladie de Verneuil : à propos de 107 cas

Hidrosadenitis supurativa y procesos afines

Long-Wave Medical Infrared Thermography: A Clinical Biomarker of Inflammation in Hidradenitis Suppurativa/Acne Inversa

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