“…ADDRESS FOR CORRESPONDENCE: Paula Jorge, Centre for Medical Genetics Doutor Jacinto Magalhães, National Health Institute Doutor Ricardo Jorge, Molecular Genetics Unit (UMO-P), Praça Pedro Nunes, 88, 4099-028 Porto, Portugal. E-mail: paula.jorge@ insa.min-saude.pt other hand, several particular complications, such as twinto-twin transfusion syndrome (TTTS) seem to occur at a significant rate in monozygotic twin pregnancies (Suetersa & Oepkes, 2005;Tong et al, 2004). Chorionicity, which refers to the type of placentation, can be determined routinely by ultrasound during the first trimester of pregnancy; however, in the second trimester the determination of chorionicity becomes more complex (Antsaklis & Partsinevelos, 2008;Tong et al, 2004).…”