Ultrasound elastography in thyroid disease

Dudea, Sorin M; Botar-Jid, Carolina

doi:10.11152/mu.2013.2066.171.smd

Cited by 72 publications

(94 citation statements)

References 122 publications

(274 reference statements)

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“…As a result of the inflammatory process, temporary or permanent impairment of thyroid function usually follows. The different forms of thyroiditis may be clearly distinguished on the basis of clinical findings, a few laboratory values, and the ultrasound results [37]. US guided FNA with cytological examination is rarely needed.…”

Section: Diffuse Thyroid Disease (Dtd)mentioning

confidence: 99%

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

et al. 2017

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Accurate differentiation of focal thyroid nodules (FTL) and thyroid abnormalities is pivotal for proper diagnostic and therapeutic work-up. In these two part articles, the role of ultrasound techniques in the characterization of FTL and evaluation of diffuse thyroid diseases is described to expand on the recently published World Federation in Ultrasound and Medicine (WFUMB) thyroid elastography guidelines and review how this guideline fits into a complete thyroid ultrasound exam.

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Section: Diffuse Thyroid Disease (Dtd)mentioning

confidence: 99%

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

et al. 2017

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“…When a thyroid nodule was identified (based on perceived contrast between the echogenicity of thyroid nodule and adjacent thyroid parenchyma), multiple transverse, and longitudinal sonograms of the nodule were obtained. Each nodule was assessed for suspicious grey scale sonographic features [1,21,29,30] including absent halo sign, microcalcification, hypoechogenicity, internal solid echotexture, tall to width ratio >1, and irregular margins (Figures 1 and 2). thyroiditis, grave's disease, and sub-acute thyroiditis), which were associated with increased thyroid parenchymal stiffness.…”

Section: Ultrasound Examination Of Thyroid Glandmentioning

confidence: 99%

“…Contrarily, shear wave elastography (SWE) is less operator-dependent and more reproducible than SE, and it provides quantitative assessment in the form of elasticity indices (E maximum , E mean , E minimum ). SWE uses focused ultrasound impulses at varying depths in tissue to induce tissue displacement and results in the generation of shear waves which propagate laterally [21]. Shear waves travel faster in harder medium than in softer counterpart, and their velocity is directly proportional to the square root of Young's modulus.…”

Section: Introductionmentioning

confidence: 99%

Shear Wave Elastography Combining with Conventional Grey Scale Ultrasound Improves the Diagnostic Accuracy in Differentiating Benign and Malignant Thyroid Nodules

et al. 2017

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Shear wave elastography provides information about the stiffness of thyroid nodules that could be a new indicator of malignancy. The current study aimed to investigate the feasibility of using shear wave elastography (SWE) alone and in conjunction with grey scale ultrasound (GSU) to predict malignancy in 111 solitary thyroid nodules. Malignant thyroid nodules tended to have microcalcification, hypoechogenicity, tall to width ratio >1, and irregular borders (p < 0.05). SWE indices (E maximum and E mean ) of malignant nodules (median ± standard error: 85.2 ± 8.1 kPa and 26.6 ± 2.5 kPa) were significantly higher than those of benign nodules (median ± standard error: 50.3 ± 3.1 kPa and 20.2 ± 1 kPa) (p < 0.05). The optimal cut-off of E maximum and E mean for distinguishing benign and malignant nodules was 67.3 kPa and 23.1 kPa, respectively. Diagnostic performances for GSU + E maximum , GSU + E mean , GSU, E maximum and E mean were: 70. 4%, 74.1%, 96.3%, 70.4% and 74.1% for sensitivity, 83.3%, 79.8%, 46.4%, 70.2%, and 66.7% for specificity, and 80.2%, 78.4%, 58.5%, 70.3%, and 68.5% for accuracy, respectively. Our results suggested that combining GSU with SWE (using E maximum or E mean ) increased the overall diagnostic accuracy in distinguishing benign and malignant thyroid nodules.

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“…[1][2][3][4][5][6][7][8][9][10][11] Sonoelastography (SE), a newer imaging tool in combination with ultrasound (also known as real time elastography [RTE]) has become one of the most important addition to the armamentarium of sonographic techniques in the last decade. [13,14] Although, not yet routinely used in urology clinical practice, previous studies have shown its usefulness in the differential diagnosis of breast, thyroid and prostate pathologies along with its role in diagnosing and staging acute appendicitis. [13][14][15][16] Sonoelastography maps the elastic property of soft tissues examined [16] which propelled us to use this technique in the evaluation of anterior urethral strictures not only for length but also for degree of spongiofibrosis and periurethral pathologies.…”

Section: Introductionmentioning

confidence: 99%

“…[13,14] Although, not yet routinely used in urology clinical practice, previous studies have shown its usefulness in the differential diagnosis of breast, thyroid and prostate pathologies along with its role in diagnosing and staging acute appendicitis. [13][14][15][16] Sonoelastography maps the elastic property of soft tissues examined [16] which propelled us to use this technique in the evaluation of anterior urethral strictures not only for length but also for degree of spongiofibrosis and periurethral pathologies. [1,2,5] Hence in the present study, we sought to compare the efficacy of real-time SE with SUG and RUG in the evaluation of anterior urethral strictures.…”

Section: Introductionmentioning

confidence: 99%

Comparison of sonoelastography with sonourethrography and retrograde urethrography in the evaluation of male anterior urethral strictures

Talreja

Tomar

Yadav

et al. 2016

Turkish Journal of Urology

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Objective: Retrograde urethrography (RUG) is the most common and preferred imaging modality for imaging of the anterior urethral strictures despite its well-known limitations and disadvantages. Sonourethrography (SUG) was introduced in 1988 to overcome the limitations of RUG and to provide more accurate results. As proper selection of imaging modality is very important for planning the treatment, various advances in this area are required. One of the major factors for recurrence of stricture disease is spongiofibrosis. Sonoelastography (SE) is a newer technique, tried in various other pathologies. In this study, we have used this technique for the first time to assess its efficacy in the evaluation of anterior urethral stricture disease by comparison with RUG and SUG. Material and methods:Between August 2014 and May 2015, 77 patients with clinical features of anterior urethral stricture disease were included in the study and evaluated by RUG followed by SUG and SE for stricture location, length, depth of spongiofibrosis and periurethral pathologies. The results were then correlated with operative and histopathological findings. Results:Overall diagnostic accuracy of SE, SUG, and RGU for the estimation of stricture location, and length were estimated 92.68% vs. 91.54%, 79% vs. 78.87% and 80.48% vs. 43.66%, respectively, while for depth of spongiofibrosis SE, and SUG had accuracy rates of 87.3%, 48%, respectively. The mean length measured on SE was nearest to the mean intra-operative stricture length (21.34+11.8 mm). SE findings significantly correlated with the colour of bladder mucosa on cystoscopic examination (p=0.003) whereas the association was nonsignificant (p=0.127) for difficulty in incision. While a nonsignificant correlation existed between SUG findings related both to the colour of the bladder mucosa and difficulty in incision on cystoscopy, SE findings had a significant association (p<0.001) with histopathology findings for severe degree of fibrosis. Conclusion:Sonoelastography estimates stricture site and length better in comparison with RUG and SUG. It estimates degree of spongiofibrosis which serves as an important prognostic factor for stricture recurrence more accurately than SUG.

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Ultrasound elastography in thyroid disease

Cited by 72 publications

References 122 publications

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

Shear Wave Elastography Combining with Conventional Grey Scale Ultrasound Improves the Diagnostic Accuracy in Differentiating Benign and Malignant Thyroid Nodules

Comparison of sonoelastography with sonourethrography and retrograde urethrography in the evaluation of male anterior urethral strictures

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