Ultrasound biomicroscopy of Chinese eyes with iridocorneal endothelial syndrome

Zhang, M

doi:10.1136/bjo.2005.074864

Cited by 25 publications

(16 citation statements)

References 26 publications

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“…4 Anterior segment UBM is a useful tool for grading the extent of iris atrophy, peripheral anterior synechiae, and proliferative changes in the angle structure. 4,11 Zhang et al, 12 reporting the results of UBM analysis of 21 patients with ICE syndrome, showed that patients with Cogan-Reese syndrome presented more peripheral anterior synechiae with higher IOP elevation, severe glaucoma, and a greater failure rate of filtering surgery than in the other clinical variants of ICE syndrome. They concluded that UBM is a fast and effective diagnostic method to explore the extent of affected structures in this syndrome and its subtypes and found that UBM analysis has a higher sensitivity than slit-lamp gonioscopy in detecting peripheral anterior synechiae and iris atrophy in patients with advanced Cogan-Reese syndrome.…”

Section: Discussionmentioning

confidence: 99%

Cogan-Reese syndrome: image analysis with specular microscopy, optical coherence tomography, and ultrasound biomicroscopy

et al. 2019

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Iridocorneal endothelial (ICE) syndrome is a progressive clinical spectrum of corneal endothelial abnormalities affecting the cornea, iris, and iridocorneal angle. Three clinical variations are recognized: essential (progressive) iris atrophy, Chandler syndrome, and Cogan-Reese syndrome. Direct slit-lamp visualization of the cornea and anterior segment in cases of ICE syndrome is inadequate for precise and objective assessment of the affected structures. We describe the evolution of corneal and anterior segment structural changes in a woman with Cogan-Reese syndrome using three different methods of image analysis: specular microscopy, anterior segment optical coherence tomography, and ultrasound biomicroscopy.

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Section: Discussionmentioning

confidence: 99%

Cogan-Reese syndrome: image analysis with specular microscopy, optical coherence tomography, and ultrasound biomicroscopy

et al. 2019

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“…31 Zhang M et al 32 compared UBM findings of anterior segment between normal subjects and three clinical types of ICE syndrome: progressive iris atrophy (PIA), Chandler's syndrome (CS), and Cogan-Reese syndrome (CRS). UBM was found to be more effective in detecting peripheral anterior synechiae (PAS) and iris atrophy than slit lamp microscopy and gonioscopy, mainly because of corneal edema in patients with CS.…”

Section: Determining the Mechanism Of Secondary Glaucomamentioning

confidence: 99%

Ultrasound Biomicroscopy in Glaucoma: An Update

Dada¹,

Gaurav²,

Mishra³

2008

JOCGP

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UBM is a high-frequency ultrasound technology that provides exceptionally detailed two-dimensional gray-scale images of the various anterior segment structures and evaluates them both quantitatively and qualitatively. It allows noninvasive in vivo imaging of structural details of the anterior ocular segment at near microscopic resolution and thus, there are many other applications of this new imaging method.This review outlines the uses of UBM in diagnosis and management of glaucoma.

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“…The diagnosis of ICE syndrome is based on the presence of clinical abnormalities involving the corneal endothelium, anterior chamber angle, and iris, often confirmed with imaging modalities of specular microscopy, confocal microscopy, ultrasound biomicroscopy, and anterior segment optical coherence tomography. [9][10][11][12] Occasionally, the features are subtle and this condition is overlooked. Laganowski and coworkers 6 evaluated 33 patients with ICE syndrome-related secondary glaucoma and noted that the underlying diagnosis of ICE syndrome was initially overlooked in 17 (68%).…”

mentioning

confidence: 99%

Iridocorneal Endothelial Syndrome Masquerading as Iris Melanoma in 71 Cases

Shields

Shields²,

Viloria³

et al. 2011

Arch Ophthalmol

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Objective: To describe the clinical features of iridocorneal endothelial (ICE) syndrome in a group of patients referred because of suspected iris melanoma. Methods: In a noncomparative case series, we performed medical record review for clinical features of ICE syndrome in 71 patients. Results: At presentation, the median patient age was 54 years. All patients were referred for evaluation of a pigmented iris mass, suspected to be a melanoma. The iris color was blue or green in 51 (72%) and brown in 20 (28%). The mass proved to be a combination of iris stromal atrophy in 41 cases (58%) with exposure or loss of the underlying iris pigment epithelium; ectropion iridis in 24 (34%), imparting a disfigured iris with darkbrown color; iris nodules in 5 (7%); traction elevation with iris distortion from peripheral anterior synechia in 57 (80%); and corectopia in 53 (75%), a feature commonly found with iris melanoma. The mean extent of iris atrophy was 2 clock hours. Ectropion iridis was unidirectional in 10 and multidirectional in 14. Additional features of ICE included corneal endothelial guttata-like changes in 33 (46%), corneal edema in 7 (10%), iris pigment epithelial transillumination defects in 12 (17%), polycoria in 1 (1%), and secondary glaucoma with intraocular pressure higher than 22 mm Hg in 7 (10%). Conclusions: Iridocorneal endothelial syndrome can simulate iris melanoma. Features more suggestive of ICE syndrome include corneal endothelial guttata-like changes and edema, peripheral anterior synechia, multidirectional ectropion iridis, and iris atrophy.

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Ultrasound biomicroscopy of Chinese eyes with iridocorneal endothelial syndrome

Cited by 25 publications

References 26 publications

Cogan-Reese syndrome: image analysis with specular microscopy, optical coherence tomography, and ultrasound biomicroscopy

Cogan-Reese syndrome: image analysis with specular microscopy, optical coherence tomography, and ultrasound biomicroscopy

Ultrasound Biomicroscopy in Glaucoma: An Update

Iridocorneal Endothelial Syndrome Masquerading as Iris Melanoma in 71 Cases

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