Ultrasound biomicroscopy measurement of Schlemm's canal in pediatric patients with and without glaucoma

Tandon, Anika; Watson, Caroline; Ayyala, Ramesh S.

doi:10.1016/j.jaapos.2017.03.011

Cited by 16 publications

(43 citation statements)

References 5 publications

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“…In the Tandon et al. () study, a trend was noted for smaller SC diameters in children <2 years of age ( n = 10). However, as recognized by the authors, their sample size was too small to establish this link.…”

Section: Discussionmentioning

confidence: 88%

“…The only available SC measurements available for healthy children provided in the UBM study by Tandon et al. () indicate a mean SC diameter in nonglaucomatous eyes of 142 ± 33.2 μ m (range 90–196). These diameters are smaller than those acquired by FD‐OCT in our study subjects.…”

Section: Discussionmentioning

confidence: 99%

“…; Tandon et al. ). Thus, a better understanding of the aqueous humour outflow pathway in normal conditions is needed (Huang et al.…”

Section: Introductionmentioning

confidence: 99%

“…; Tandon et al. ). However, this invasive and time‐consuming technique has been superseded by optical coherence tomography (OCT) which offers much improved resolution (Fuest et al.…”

Section: Introductionmentioning

confidence: 99%

“…; Tandon et al. ). This lack of literature data also means that the possible effects of several factors such as gender, age, refractive error, angle or TM measurements on the size of the anterior chamber angle and its structures have yet to be addressed.…”

Section: Introductionmentioning

confidence: 99%

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Schlemm's canal measured by optical coherence tomography and correlation study in a healthy Caucasian child population

Fernández‐Vigo

Kudsieh²,

De‐Pablo‐Gómez‐de‐Liaño

et al. 2018

Acta Ophthalmologica

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Purpose To measure the Schlemm's canal (SC) in vivo by Fourier‐domain optical coherence tomography (FD‐OCT) in a Caucasian paediatric population. Methods Participants of this cross‐sectional study were 290 healthy children. In the right eye of each child, SC cross‐sectional diameter and area measurements were made with the FD‐OCT instrument RTVue® (Optovue Inc, Fremont, CA, USA) in the nasal and temporal quadrants. These SC variables were then assessed for correlation with the factors age, gender, refractive error, anterior chamber angle and trabecular meshwork (TM) metrics. Finally, the reproducibility of the SC measurements was assessed in 30 of the participants. Results Mean participant age was 10.7 ± 3.4 years (range 3–18). SC diameters could be measured in both quadrants in 70.6% and 70.4% of subjects, respectively. Mean SC diameters were similar (p = 0.125) for the temporal and nasal quadrants: 266.7 ± 84.1 μm (range 131–509) and 273.2 ± 77.3 μm (range 124–486), respectively. Mean SC areas were also similar (p = 0.167) for the two quadrants: 9975 ± 3514 μm2 (range 4000–23 000) versus 9688 ± 3297 μm2 (range 3000–24 000). No differences were detected in SC measurements according to gender, refractive error or angle and TM measurements (R ≤ 0.116; p ≥ 0.125). The exception was age which was directly correlated with SC size (p ≤ 0.041). The reproducibility of the SC measurements was excellent (intraclass correlation coefficients ≥0.936). Conclusion FD‐OCT allows the identification of the SC in children. Our data indicate an increase in SC size produced with age.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

“…; Tandon et al. ). Thus, a better understanding of the aqueous humour outflow pathway in normal conditions is needed (Huang et al.…”

Section: Introductionmentioning

confidence: 99%

“…; Tandon et al. ). However, this invasive and time‐consuming technique has been superseded by optical coherence tomography (OCT) which offers much improved resolution (Fuest et al.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations