“…However, very little is known about the in vivo morphology of the cornea during acute hydrops and how it affects the response to therapy. 13,14 In our previous study, we found that although intracameral C 3 F 8 significantly reduced the duration of corneal edema in eyes with acute corneal hydrops, the effect was widely variable (8.1 6 5.5 weeks). 15 Considering this, we hypothesized that factors such as size of the DM break, depth of the DM detachment, and initial corneal thickness may influence the duration of corneal edema in addition to the effect of any treatment.…”