Ultrasound-based radial and longitudinal strain estimation of the carotid artery: a feasibility study

Larsson, Matilda; Kremer, Florence; Claus, Piet; Kuznetsova, Tatiana; Brodin, Lärs-Åke; D'hooge, Jan

doi:10.1109/tuffc.2011.2074

Cited by 58 publications

(40 citation statements)

References 38 publications

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“…These results confirm previous studies reporting the feasibility of estimating longitudinal strain of the carotid artery wall both in-silico [11] and invitro [12].…”

Section: Discussionsupporting

confidence: 91%

“…Speckle tracking analysis was performed on the envelopedetected data throughout three consecutive cardiac cycles using the previously developed algorithm [13]. Twodimensional (2D) motion estimation was performed across subsequent frames using normalized cross-correlation (kernel width: 5 wavelengths (λ), kernel length: 2λ, 40% axial and lateral overlap, spline interpolation for detection of sub-sample motion).…”

Section: Speckle Tracking Analysismentioning

confidence: 99%

“…Recently, we showed the feasibility of ultrasound-based speckle tracking to assess carotid longitudinal strain in-silico [11] and in-vitro [12], but validation in the more challenging invivo setting is still lacking. Accordingly, the aim of this study was to validate longitudinal strain assessment in the common carotid artery in an animal setup.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Assessment of longitudinal strain in the carotid artery wall using ultrasound-based Speckle tracking - Validation in a sheep model

Larsson

Verbrugghe

Smoljkic

et al. 2013

2013 IEEE International Ultrasonics Symposium (IUS)

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Abstract-Assessment of strain in the longitudinal direction of the arterial wall has been suggested to improve the evaluation of arterial stiffness and atherosclerosis. Recently, we showed the feasibility of ultrasound speckle tracking to assess carotid longitudinal strain in-silico and in-vitro. However, validation in the more challenging in-vivo setting is still lacking. The aim of this study was to validate longitudinal strain assessment in the common carotid artery (CCA) in an animal setup. The left CCAs of five sheep were exposed during Isoflurane anesthesia and sonomicrometry crystals were sutured onto the artery wall to obtain reference longitudinal strain. Ultrasound long-axis images were recorded at baseline and hypertension (Phenylephrine) and an in-house speckle tracking algorithm was applied to estimate longitudinal strain. The estimated strain curves varied cyclically throughout the cardiac cycles, showing a lengthening of the arterial segment in systole. A significant correlation between peak systolic estimated and reference strain was found (r=0.95, p < 0.001). The results indicate the feasibility of arterial longitudinal strain assessment in-vivo using ultrasound speckle tracking.

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“…These results confirm previous studies reporting the feasibility of estimating longitudinal strain of the carotid artery wall both in-silico [11] and invitro [12].…”

Section: Discussionsupporting

confidence: 91%

Section: Speckle Tracking Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of longitudinal strain in the carotid artery wall using ultrasound-based Speckle tracking - Validation in a sheep model

Larsson

Verbrugghe

Smoljkic

et al. 2013

2013 IEEE International Ultrasonics Symposium (IUS)

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“…Techniques for noninvasive estimation of arterial wall strains by ultrasound also exist [5][6][7][8][9][10]. However, most of these techniques allow strain estimation in 2D imaging planes only, because they are based on conventional focused ultrasound acquisition, which frame rates are too low for extension to 3D.…”

Section: Introductionmentioning

confidence: 99%

Performance evaluation of compounding and directional beamforming techniques for carotid strain imaging using plane wave transmissions

Hansen

Stuart

Hoyos

et al. 2014

2014 IEEE International Ultrasonics Symposium

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Abstract-Carotid strain imaging in 3D is not possible with conventional focused imaging, because the frame rate is too low. Plane wave ultrasound provides sufficiently high frame rates, albeit at the cost of image quality, especially in the off-axis direction due to the lack of focusing. Multiple techniques have been developed to cope with the low off-axis image quality when performing 2D (and in future 3D) motion estimation: cross correlation with directional beamforming (with or without RF (coherent) compounding) and displacement compounding. This study compares the precision of these techniques using linear array ultrasound data of a pulsating concentric homogeneous artery simulated using Field II. The transducer (f c = 9 MHz, pitch = 197.9 µm, 192 elements, f s = 180 MHz) transmitted plane waves at 3 sequentially alternating angles (0°, +θ, -θ) at a PRF of 2 kHz. Simulations were repeated for θ ranging from 1° to 20° with increments of 1°. Displacements were estimated for frame intervals of 1/15th s, tracked, and cumulated from diastole to systole using either displacement compounding, or directional beamforming optionally enhanced by RF compounding. 1D directional beamforming with RF compounding and 2D displacement compounding with θ = ~20° performed equally and best with a relative root-mean-squared error of ~2% with respect to the analytical solution. The mean and standard deviation of the estimated motion direction for 2D displacement compounding with θ = 20° was 0.03° +/-1.43°. Since displacement compounding requires no assumptions regarding the motion direction, this technique seems the best option for plane wave carotid strain imaging.

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“…However, extensive validation via reference methods are still missing. Recently, our group published a speckle tracking algorithm successfully estimating strain in the wall of a carotid artery phantom [8]. The aim of this study was to use the same speckle tracking algorithm to validate radial and longitudinal strain in plaques via sonomicrometry, and compare the measured plaque and arterial wall strain.…”

Section: Introductionmentioning

confidence: 99%

Speckle tracking strain estimation of a carotid artery plaque phantom - Validation via sonomicrometry

Widman

Caidahl

Heyde

et al. 2013

2013 IEEE International Ultrasonics Symposium (IUS)

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Abstract-Current clinical ultrasound-based methods for plaque characterization are limited to visual assessment of plaque echogenicity creating demand for quantitative diagnostic tools. Our objective was to validate radial and longitudinal speckle tracking (ST) strain in phantom plaques via sonomicrometry (sono), and to compare the peak plaque and arterial wall strain. Four carotid artery gel-phantoms with a soft wall inclusion, mimicking a vulnerable plaque, were constructed. The phantoms were connected to a programmable pump simulating a carotid flow. Cineloops were acquired using a GE Vivid E9 where radial and longitudinal strain were calculated using a normalized crosscorrelation ST algorithm. The region of interest was adjusted according to the plaque size. Sonomicrometry was used as a reference measurement. The correlation between estimated mean peak strain and the reference peak strain was r = 0.96 (p < 0.001) radially and r = 0.75 (p ≤ 0.005) longitudinally. The soft plaque exhibited 35.1% (SD 16.9%) greater radial (p < 0.001) and 88.6% (SD 72.0%) greater longitudinal (p < 0.001) peak strain than the arterial wall when measured with speckle tracking. It was possible to estimate plaque strain by ST and to distinguish a soft plaque from the vessel wall via strain measurements.

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Ultrasound-based radial and longitudinal strain estimation of the carotid artery: a feasibility study

Cited by 58 publications

References 38 publications

Assessment of longitudinal strain in the carotid artery wall using ultrasound-based Speckle tracking - Validation in a sheep model

Assessment of longitudinal strain in the carotid artery wall using ultrasound-based Speckle tracking - Validation in a sheep model

Performance evaluation of compounding and directional beamforming techniques for carotid strain imaging using plane wave transmissions

Speckle tracking strain estimation of a carotid artery plaque phantom - Validation via sonomicrometry

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