Ultrasound‐assisted green synthesis of Cu‐based complexes of β‐cyclodextrin and their SOD‐like activity

Abstract

A novel Cu-Zn β-cyclodextrin (CuZn/β-CD) model compound was synthesized under ultrasound irradiation to mimic the functionality of copper zinc superoxide dismutase (CuZnSOD). For comparison, Cu/β-CD and Zn/β-CD complexes were also synthesized via a sonochemical approach. The obtained complexes were characterized by FTIR, ICP-OES, UV-vis and Scanning electron microscopy-Energy dispersive X-ray (SEM-EDX) techniques. The SOD activity of the complexes was evaluated by a pyrogallol autoxidation method. These enzyme-mimetic materials scavenge ambient free radicals, with the potential to provide significant antioxidant protection (scavenging ability > 70%).