Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis

Zu, Ge; Zhang, Rongrui; Yang, Lei; Ma, Chunhui; Zu, Yuangang; Wang, Wenjie; Zhao, Chunjian

doi:10.3390/ijms130911027

Cited by 87 publications

(49 citation statements)

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“…For example, UAE shown to be highly eicient in the extraction of carnosic acid and rosmarinic compared to classical methods of extraction [94]. In a recent study [95], the maximum extraction yield of total polyphenols (13.2 mg/g dry weight) from spruce wood bark was obtained when UAE system was used.…”

Section: The Ultrasound-assisted Extraction (Uae) Methodsmentioning

confidence: 99%

Phenolics in Foods: Extraction, Analysis and Measurements

Aires¹

2017

Phenolic Compounds - Natural Sources, Importance and Applications

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The increasing consumers demands to acquire healthier fruits and vegetables as well as the urgency in looking to natural compounds with antioxidant activity and enhanced antimicrobial activity against antibiotic-resistant pathogenic bacterial strains have encouraged a quick expansion of research studies about enhanced phenolic extraction and identiication methods. Considering the importance of phenolics as natural compounds with antioxidant and antimicrobial activity, this chapter aims to present the most updated information about extraction methods, ranging from the traditional to the most advanced processes, as well as the access to the modern methods used in the identiication and quantiication of phenolics. The main goal of this chapter is to provide the reader with a broad view on the diferent protocols used to extract, identify and quantify phenolic compounds from diferent kinds of foods, including fruits and vegetables.Keywords: phytochemicals, extraction, determination, colorimetric methods, HPLC, HPLC-MS IntroductionThe growing resistance of pathogenic bacterial isolates against the traditional chemical antibiotics as well as the resurgent of old disappeared diseases associated with the constant consumers' demanding of healthier, nutritious and safe food has led the researchers to focus on searching for new, safe and efective molecules. One class of such molecules is the class of polyphenols. Polyphenols are a ubiquitous class of compounds largely present in plants as their secondary metabolites, which are synthesized during their normal development [1] in response to several stressful biotic and abiotic factors [2,3]. This class of compounds are a much diversiied group derived from the amino acids phenylalanine and tyrosine and The results from the last decade's research have shown that polyphenols have important beneicial properties for human health, including antioxidative, antiaging, antibacterial and antimutagenic [7][8][9][10][11]. Moreover, the recent evidence of their interaction with proteins, DNA and other biological molecules has enhanced their exploitation for the production of new natural product-derived therapeutic agents. Despite these advantages, several limitations still persist, particularly those related with their extraction eiciency, which afects the large-scale use of some of these substances. The diiculties in screening, extracting, separation and purifying these compounds have increased the development of new and modern methods to address these limitations. In this context, the aim of this chapter is to present an updated review about sources, technologies and methods that have been developed until now to improve the extraction, detection, separation and full characterization of such beneicial compounds, with special emphasis to their possible application in the design of nutraceuticals and functional food products. Foods as natural resources of phenolicsPolyphenols have been exhaustively studied in their diferent natural matrices such as fruits, vegetables, teas, algae a...

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Section: The Ultrasound-assisted Extraction (Uae) Methodsmentioning

confidence: 99%

Phenolics in Foods: Extraction, Analysis and Measurements

Aires¹

2017

Phenolic Compounds - Natural Sources, Importance and Applications

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show abstract

“…Anthocyanins and phenolic compounds were extracted from grape peel using UAE and the extraction process was optimized with reference to solvent, extraction temperature and time (Ghafoor et al, 2011(Ghafoor et al, , 2009). Phenolcarboxylic acids, carnosic acid and rosmarinic acid were extracted from Rosmarinus officinalis using Ionic liquid based UAE technique which was proved to have high efficiency and shorter extraction time than conventional extraction methods (Zu et al, 2012).…”

Section: Ultrasound-assisted Extraction (Uae)mentioning

confidence: 99%

Techniques for extraction of bioactive compounds from plant materials: A review

Azmir

Zaidul

Rahman

et al. 2013

Journal of Food Engineering

2,047

1,179

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“…Throughout literature, at a laboratory scale, extraction of RA and CA from rosemary leaves has been investigated using different technologies: conventional solvent extraction [10], microwave [11][12][13], ultrasound assisted extraction [12,[14][15][16], supercritical and subcritical fluid extraction [16][17][18] pressurized liquid extraction [18,19], deodorization by Instant Controlled Pressure drop [20] or extraction with ionic liquids [21]. Table 1 details the experimental conditions of the mentioned processes.…”

Section: Introductionmentioning

confidence: 99%