Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes

Trojanowska, Anna; Tsibranska, I.; Dzhonova, Daniela; Wroblewska, Michalina; Haponska, Monika; Jovančić, Petar; Marturano, Valentina; Tylkowski, Bartosz

doi:10.1016/j.cherd.2019.05.018

Cited by 34 publications

(19 citation statements)

References 33 publications

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“…On the contrary, the active compound extraction from N. lappaceum also depends on the extraction technique, and generally, the ultrasound technique shows a greater extraction capacity. is technique improves the efficiency of the extraction solvent and has excellent destructive effects on a matrix because it alters the fluid around the solid particles, via cavitation processes, and the internal structure, by disrupting cell walls and/or enlarging its pores, thus allowing the solvent to better penetrate into the cell and release the target molecules [67,68]. Additionally, this technique is economical and environmentally friendly and presents the ability to produce concentrated extracts in a time-efficient manner [68].…”

Section: Chemical Composition Of the N Lappaceum Peelmentioning

confidence: 99%

Active Compound Identification in Extracts of N. lappaceum Peel and Evaluation of Antioxidant Capacity

Monrroy

Araúz

García

2020

Journal of Chemistry

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Nephelium lappaceum and its by-products have great potential in the agricultural, pharmaceutical, and food industries. Some studies have shown that N. lappaceum by-products exhibit antimicrobial, antioxidant, antidiabetic, and anticancer properties. However, studies focused on identifying these compounds are rare. The availability of polyphenolic compounds can vary according to environmental conditions, soil, plant variety, and agronomic management. Therefore, in this study, the active compounds in extracts of the N. lappaceum peel were identified, and their antioxidant properties were evaluated using various extraction solvents and both ultrasonic and boiling extraction techniques. The chemical characterization of the N. lappaceum peel exhibited carbohydrate and reducing sugar contents of 12 and 2%, respectively. Phytochemical analysis indicated the presence of flavonoids, tannins, terpenes, and steroids. The total phenolic and flavonoid contents and total antioxidant capacity were the highest in the hydroethanolic extract obtained by ultrasound, with values of 340 mg gallic acid equivalents g−1, 76 mg quercetin equivalents g−1, and 2.9 mmol of Trolox equivalents g−1, respectively. Contrarily, the total anthocyanin content was higher in the acid extract obtained by ultrasound, with a value of 0.7 mg cyanidin-3-O-glucoside equivalents g−1. A total of 18 compounds—including hydroxybenzene, phenolic acid, flavonoids, fatty acids (saturated, unsaturated, and ester), vitamin, arenecarbaldehyde, and phthalate—were identified for the first time in the N. lappaceum peel using gas chromatography-mass spectrometry. The identified compounds have been previously isolated from other plants and reportedly exhibit anticancer, anti-inflammatory, antimicrobial, and antioxidant activities. Thus, the N. lappaceum peel was shown to be a potential source of bioactive compounds of immense importance in the pharmacological and food industries.

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Section: Chemical Composition Of the N Lappaceum Peelmentioning

confidence: 99%

Active Compound Identification in Extracts of N. lappaceum Peel and Evaluation of Antioxidant Capacity

Monrroy

Araúz

García

2020

Journal of Chemistry

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“…Meanwhile, the highest TAC from columella (1.52 mg/g DW) was obtained with 10 min of extraction, 40% amplitude, and 0.4 s of pulse-cycle. The effect of UAE on the extraction of ACGs is discussed as follows: the application of ultrasonic waves had mechanical and thermal effects producing cavitation in the solvent; the microbubbles interacted with the vegetal cells and modify their structure by breaking down the cell walls and/or increasing the size of cell pores, resulting in a faster dissolution of the bioactive compounds in the solvent [21][22][23]. On the other hand, the differences of the UAE conditions for extracting ACGs also depend on the structural chemical composition of each raw material and the physical-mechanical phenomenon generated by each UAE combination.…”

Section: Effect Of Ultrasound-assisted Extraction (Uae) On the Total mentioning

confidence: 99%

Ultrasound-Assisted Extraction of Total Acetogenins from the Soursop Fruit by Response Surface Methodology

et al. 2020

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The soursop fruit or Annona muricata (A. muricata) fruit is recognized by its bioactive compounds and acetogenins (ACG) are among the most important. The effect of ACGs, with greater importance in health, is that they present anti-tumor activity; however, the methods of extraction of ACGs are very slow and with a high expenditure of solvents. To our knowledge, there is no report of an optimal method for the extraction of acetogenins from the Annonaceae family by ultrasound-assisted extraction (UAE); therefore, the aim was to find the best UEA conditions of acetogenins from A. muricata fruit (peel, pulp, seed, and columella) by using response surface methodology. The effect of amplitude (40%, 70%, and 100%), time (5, 10, and 15 min), and pulse-cycle (0.4, 0.7, and 1 s) of ultrasound at 24 kHz was evaluated on the total acetogenin content (TAC). Optimal extraction conditions of acetogenins (ACGs) with UEA were compared with the extraction of ACGs by maceration. The optimal UEA conditions in the A. muricata pulp and by-products were dependent on each raw material. The highest TAC was found in the seed (13.01 mg/g dry weight (DW)), followed by the peel (1.69 mg/g DW), the pulp (1.67 mg/g DW), and columella (1.52 mg/g DW). The experimental TAC correlated well with the model (Adjusted R2 with values between 0.88 and 0.97). The highest effectiveness in ACG extraction was obtained in seeds and peels using UEA compared to extraction by maceration (993% and 650%, respectively). The results showed that A. muricata by-products are an important source of ACGs and that UAE could be a viable alternative, with high potential for large-scale extraction.

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“…After 5 min, 8 mL of 7.5% (w/v) aqueous Na 2 CO 3 solution was added to the mixture and stored for two hours in the dark. The concentration of released phenols was determined by UV-Vis spectroscopy at 765 nm using a UV-1800 Shimadzu apparatus (Thermo Fisher Scientific, Waltham, MA, USA) [28]. The results were calculated as Gallic Acid Equivalents (GAE), using a standard curve obtained from previous experiments: Abs = 0.1214x + 0.1142, where Abs is the absorbance of the sample at 765 nm and x is the phenolic concentration in µgGAE/mL (R 2 = 0.9988).…”

Section: Determination Of Polyphenols Contentmentioning

confidence: 99%

Preparation and Characterization of UV-Curable Acrylic Membranes Embedding Natural Antioxidants

Rajczak

Tylkowski²,

Constantí

et al. 2020

Polymers

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We examine the behaviour of acrylic resin-based membranes containing natural anti-oxidants, such as Galla chinensis tea powder extract (TP) and Taiwanese green propolis (TGP), in different concentrations ranging between 5 and 20 wt %. Membrane morphology was investigated by means of Environmental Scanning Electron Microscopy (ESEM), while the UV-curing reaction was monitored by Fourier-Transform Infra-red (FTIR) spectroscopy. In most cases Thermogravimetric (TG), Differential Scanning Calorimetric (DSC) and Dynamo-mechanical Thermal (DMT) analyses showed that the desirable characteristics of the UV-cured acrylic resin are not substantially altered by the presence of the organic fillers. The release kinetics of polyphenols and flavonoids, determined in water for TP-containing membranes (ETx) and in ethanol/water mixture (7:3 v/v) for TGP-containing ones (EPx), was satisfactory, reaching a plateau after 24 h. Finally, preliminary antibacterial tests against S. epidermidis were performed on the membranes with higher additive amount and gave positive results for ET-type; on the contrary, no inhibitory effect was observed for the tested EP-type membranes.

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Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes

Cited by 34 publications

References 33 publications

Active Compound Identification in Extracts of N. lappaceum Peel and Evaluation of Antioxidant Capacity

Active Compound Identification in Extracts of N. lappaceum Peel and Evaluation of Antioxidant Capacity

Ultrasound-Assisted Extraction of Total Acetogenins from the Soursop Fruit by Response Surface Methodology

Preparation and Characterization of UV-Curable Acrylic Membranes Embedding Natural Antioxidants

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