Ultrasound assessment of tissue integration of the crosslinked hyaluronic acid filler VYC‐25L in facial lower‐third aesthetic treatment: A prospective multicenter study

Abstract

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Ultrasound patterns of different dermal filler materials used in aesthetics

“…Nevertheless, 1-month after treatment, ultrasound images showed a typical complete heterogeneous pattern, which indicated a total integration of the VYC-25L into the tissue. 20 The HA-based fillers ultrasound pattern found immediately after injection is similar to that described by Schelke et al 7 However, the ultrasound pattern exhibited by HA-based fillers once integrated into the tissue was totally different, becoming similar to the healthy skin/subcutaneous tissue pattern.…”

“…The results of this found that, immediately after treatment, ultrasound images were characterized by a globular and poorly define pattern, with anechoic images indicative of liquid content. Nevertheless, 1‐month after treatment, ultrasound images showed a typical complete heterogeneous pattern, which indicated a total integration of the VYC‐25L into the tissue 20 …”

“…Regarding HA‐based fillers, ultrasound pattern depends on time elapsed from injection. A recent study published by our group evaluated, by means ultrasound examinations, tissue biointegration of an HA‐based dermal filler (VYC‐25L, Juvéderm Volux ® ; Allergan plc, Dublin, Ireland) 20 . The results of this found that, immediately after treatment, ultrasound images were characterized by a globular and poorly define pattern, with anechoic images indicative of liquid content.…”

An expert consensus report on the clinical use of the Vycross® hyaluronic acid VYC‐25 L filler

“…Heterogeneous patterns are evident upon ultrasound examination, with no residual anechoic/hypoechoic areas, indicative of the full integration of VYC-25L into the tissue 30 days after injection. 19 Irrespective of the technique used, facial analysis is the cornerstone to achieve optimal outcomes, which critically depends on understanding the underlying anatomy and the clinical implications of facial aging. 28 Moreover, when considering facial muscles, it is important not only to focus on the treatment results at rest but also in movement.…”

High-Frequency Ultrasound to Assess Activity in Connective Tissue Panniculitis

“…HFUS can be used to quantify subcutaneous tissue atrophy [ 21 , 33 ], one of the frequent sequelae in CTP [ 5 ]. In cases of esthetic restorative treatment, it would allow evaluation of the results [ 34 ]. In addition, it allows measurement of the size and depth of calcium deposits, enabling assessment of long-term treatment response [ 35 ].…”