“…Futhermore, Doppler ultrasound of the extremities allows to rule out vein thrombosis and arterial stenosis or occlusions, complications that may be associated with malignant diseases, like lymphoma, and that could be life threatening [6,7]. In the evaluation of swollen extremities, especially if monolateral, numerous differential diagnosis need to be considered and ruled out: ultrasonography can be a helpfull instrument to guide through the correct diagnosis, as indicated by several authors [8,9]. Soft tissue involvement characterized by the presence of multiple nodular lesions is a challenging condition because the origin of these alterations could be related to in ammatory or neoplastic cells.…”