Ultrasonography for Intraoperative Determination of Tumor Thickness and Resection Margin in Tongue Carcinomas

Kodama, Masaaki; Khanal, Amit; Habu, Manabu; Iwanaga, Kenjiro; Yoshioka, Izumi; Tanaka, Tatsurou; Morimoto, Yasuhiro; Tominaga, Kazuhiro

doi:10.1016/j.joms.2009.07.110

Cited by 60 publications

(56 citation statements)

References 26 publications

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“…Such diagnostic also included two reports about ultrasound, but we had to discard studies of ultrasonography, as these are focused on the detection of cervical metastases 31 or the determination of lingual tumour density at stages T1 and T2. 32 Although methods such as CT, MRI, panoramic radiography and CBCT have a high capacity for detection of mandibular bone tissue invasion in patients, we found a large variation between minimum and maximum sensitivity values. CBCT shows high sensitivity and specificity values, greater than those seen for panoramic radiography or MRI, but tends to underestimate the extent of mandibular invasion.…”

Section: Discussionmentioning

confidence: 63%

Accuracy of imaging methods for detection of bone tissue invasion in patients with oral squamous cell carcinoma

Uribe

Rojas²,

Rosas³

2013

Dentomaxillofacial Radiology

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The objective of this review is to evaluate the diagnostic accuracy of imaging methods for detection of mandibular bone tissue invasion by squamous cell carcinoma (SCC). A systematic review was carried out of studies in MEDLINE, SciELO and ScienceDirect, published between 1960 and, in English, Spanish or German, which compared detection of mandibular bone tissue invasion via different imaging tests against a histopathology reference standard. Sensitivity and specificity data were extracted from each study. The outcome measure was diagnostic accuracy. We found 338 articles, of which 5 fulfilled the inclusion criteria. Tests included were: CT (four articles), MRI (four articles), panoramic radiography (one article), positron emission tomography (PET)/CT (one article) and cone beam CT (CBCT) (one article). The quality of articles was low to moderate and the evidence showed that all tests have a high diagnostic accuracy for detection of mandibular bone tissue invasion by SCC, with sensitivity values of 94% (MRI), 91% (CBCT), 83% (CT) and 55% (panoramic radiography), and specificity values of 100% (CT, MRI, CBCT), 97% (PET/CT) and 91.7% (panoramic radiography). Available evidence is scarce and of only low to moderate quality. However, it is consistently shown that current imaging methods give a moderate to high diagnostic accuracy for the detection of mandibular bone tissue invasion by SCC. Recommendations are given for improving the quality of future reports, in particular provision of a detailed description of the patients' conditions, the imaging instrument and both imaging and histopathological invasion criteria.

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Section: Discussionmentioning

confidence: 63%

Accuracy of imaging methods for detection of bone tissue invasion in patients with oral squamous cell carcinoma

Uribe

Rojas²,

Rosas³

2013

Dentomaxillofacial Radiology

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“…3,[6][7][8][9][10] This methodology has also been useful for inspecting inflammation and tumours around the tonsils. 11 Kutluhan et al 12 reported that the pre-operative measurement of lesions for tonsillectomy by IOUS was reliable.…”

Section: Discussionmentioning

confidence: 99%

Intraoral ultrasonography of tongue mass lesions

Sugawara¹,

Takahashi²,

Kawano³

et al. 2016

Dentomaxillofacial Radiology

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Objectives: To demonstrate the usefulness of intraoral ultrasonography (IOUS) for tongue mass lesions, we analyzed surgery cases excluding squamous-cell carcinoma and leukoplakia and compared IOUS and pathological findings. Methods: We used the hospital information system and Radiology Information System to evaluate the IOUS and pathological findings of patients who underwent surgeries for tongue masses in the past 11 years. Results: Surgeries for the tongues were performed in 268 cases. Imaging examinations were carried out in 52 (19.4%) cases including 42 (15.7%) cases by IOUS. The pathological results of the surgeries were as follows: 36 cases were inflammatory lesions, 74 cases were tumours, 131 cases were hyperplasia, 8 cases were cystic lesions and 19 cases were other miscellaneous lesions. On the other hand, the number of patients who received IOUS in the same period was 87, and 42 of them had surgeries. In 32 out of the 42 (76.2%) cases, pre-operative IOUS features matched with pathological results. Most of the haemangiomas and lipomas could be diagnosed by IOUS alone. Conclusions: IOUS of the tongue revealed the nature of the lesions including the border, size, location, depth, the presence or absence of a capsule and the internal structure including vascularity of the mass. The ultrasonographic findings well reflected the histological findings. IOUS is a simple and useful technique that provides additional information beyond inspection, clarifying the internal structure, blood flow and relationships with the adjacent tissues. In this article, we indicated 11 representative cases (fibrous polyp, haemangioma, pyogenic granuloma, lipoma, liposarcoma, chondroma, lymphangioma, schwannoma, neurofibroma, pleomorphic adenoma and amyloidosis) to show the usefulness of IOUS.

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“…Songra et al [40] compared the assessment of thickness and excision margins by either US or subsequent histological analysis and concluded that US can be considered a reliable tool in assessing these parameters at the time of surgery. More recently, Kodama et al [134] successfully reached margin clearance using intraoperative US.…”

Section: Optical Techniquesmentioning

confidence: 99%

Open questions and novel concepts in oral cancer surgery

Tirelli

Zacchigna

Biasotto

et al. 2015

Eur Arch Otorhinolaryngol

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The persistence of cancerous cells after surgery in oral squamous cell carcinoma (OSCC) represents a major challenge, as it often leads to local recurrences and secondary primary tumors, which are eventually responsible for a large proportion of deaths. This persistence is currently evaluated by histological analyses. In this review we discuss some important pitfalls of the histopathological analysis, such as margin evaluation, specimen shrinkage and T staging. In addition, we critically analyze the appropriateness of current surgical techniques in relation to the concept of field cancerization. Finally, we describe some novel imaging and molecular approaches, which might be useful in tailoring surgical resections and encourage the use of OSCC animal models to explore and provide proof of concept of the feasibility and potential clinical utility of innovative surgical protocols.

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Ultrasonography for Intraoperative Determination of Tumor Thickness and Resection Margin in Tongue Carcinomas

Cited by 60 publications

References 26 publications

Accuracy of imaging methods for detection of bone tissue invasion in patients with oral squamous cell carcinoma

Accuracy of imaging methods for detection of bone tissue invasion in patients with oral squamous cell carcinoma

Intraoral ultrasonography of tongue mass lesions

Open questions and novel concepts in oral cancer surgery

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