Ultrasonographic study of left ventricular function at rest in a group of highly trained black African handball players

Dzudie, Anastase; Menanga, Alain; Hamadou, Bâ; Kengne, André Pascal; Atchou, G.; Kingué, Samuel

doi:10.1016/j.euje.2006.02.006

Cited by 20 publications

(17 citation statements)

References 21 publications

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“…In the 13 studies that directly compared athletes with controls, there were variations in the degree of matching; 11 studies matched for age, and 3 studies explicitly stated that they matched for body size. 7,27,35 One study stated that the 2 arms were matched without further specification, 20 and 2 studies did not report whether the study arms were matched. 18,36 Of the 10 studies that did not explicitly state whether they matched for body size, 4 studies provided mean values for body surface area (BSA) and/or height in controls that were either greater than or not significantly different from the values in the athletes.…”

Section: Resultsmentioning

confidence: 99%

“…A final total of 23 studies met our inclusion criteria, 7, with athletes directly compared with controls in 13 studies. 7,18,[20][21][22][23]27,29,33,35,36,38,39 The identified studies included 19 cross-sectional and 4 longitudinal studies conducted in Europe (n=14), the United States (n=6), Africa (n=2), and Iran (n=1). Across the studies, aortic root dimensions were reported in 5580 unique elite athletes comprised of 1506 endurance-trained athletes, 425 strength-trained athletes, 213 combined endurance-and strength-trained athletes, and a heterogeneous group of 3436 athletes with mixed training.…”

Section: Resultsmentioning

confidence: 99%

“…Sample sizes ranged from 11 to 1403 participants, and echocardiography was used to measure aortic root size in all studies. Aortic root was measured at the aortic valve annulus in 15 studies 7,[18][19][20][23][24][25]27,28,30,31,34,36,38,39 and at the sinuses of Valsalva in 12 studies. 7,[21][22][23][24]26,28,29,32,33,35,37 (Tables 1 and 2).…”

Section: Resultsmentioning

confidence: 99%

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A Meta-Analysis of Aortic Root Size in Elite Athletes

2013

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and atrium (Appendix I in the online-only Data Supplement). In addition, we manually reviewed the references of included studies Background-The aorta is exposed to hemodynamic stress during exercise, but whether or not the aorta is larger in athletes is not clear. We performed a systematic literature review and meta-analysis to examine whethere athletes demonstrate increased aortic root dimensions compared with nonathlete controls. Methods and Results-We searched MEDLINE and Scopus from inception through August 12, 2012, for Englishlanguage studies reporting the aortic root size in elite athletes. Two investigators independently extracted athlete and study characteristics. A multivariate linear mixed model was used to conduct meta-regression analyses. We identified 71 studies reporting aortic root dimensions in 8564 unique athletes, but only 23 of these studies met our criteria by reporting aortic root dimensions at the aortic valve annulus or sinus of Valsalva in elite athletes (n=5580). Athletes were compared directly with controls (n=727) in 13 studies. On meta-regression, the weighted mean aortic root diameter measured at the sinuses of Valsalva was 3.2 mm (P=0.02) larger in athletes than in the nonathletic controls, whereas aortic root size at the aortic valve annulus was 1.6 mm (P=0.04) greater in athletes than in controls. Conclusions-Elite athletes have a small but significantly larger aortic root diameter at the sinuses of Valsalva and aortic valve annulus, but this difference is minor and clinically insignificant. Clinicians evaluating athletes should know that marked aortic root dilatation likely represents a pathological process and not a physiological adaptation to exercise. .).The online-only Data Supplement is available with this article at http://circ.ahajournals.org/lookup/suppl

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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A Meta-Analysis of Aortic Root Size in Elite Athletes

2013

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“…(26) In the Framingham study, leisure time physical activity was associated with increased LV mass in men but not in women. (27) In an echocardiographic study by Dzudie, et al (28) on Cameroonian asymptomatic handball players, left ventricular mass indexed, relative wall thickness, left ventricular end diastolic diameter and left atrial diameter were signifi cantly greater in athletes compared to controls.…”

Section: Physiological Hypertrophymentioning

confidence: 99%

Hypertensive heart disease in Africa

Aje

Adebiyi

Falase

2017

SAHJ

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There are few studies in Africa on blood pressure control.However, all the studies tended to show that blood pressure control in Africa is less than optimal. For example, in a study by Isezuo, et al. (10) 42.7% blood pressure control rate was achieved among hypertensives managed in a specialised health setting in Nigeria. Data from the United States (11) however revealed that advanced countries have not fared better as only 27% of hypertensives had good blood pressure control which was still far below the goal of 50%. In another study in Cape Town, South Africa, Rayner, et al. (12) found that only 39.8% of hypertensives achieved good blood pressure control rate, a fi gure which again was still less than optimal. LEFT VENTRICULAR HYPERTROPHYLeft ventricular hypertrophy (LVH) is the best studied marker of hypertensive heart disease.

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“…29 The effect of ACE I/D gene polymorphism on LV mass in our study is obvious; there is a summative effect of the presence of D allele, with DD genotype carriers showing the highest LV mass, II showing the least and ID showing an intermediate value. Previous studies showed similar results in response to 10-week physical training in male Caucasians 19,30 as well as in strength-trained elite athletes.…”

Section: Discussionmentioning

confidence: 86%

Angiotensin-converting enzyme I/D gene polymorphism affects early cardiac response to professional training in young footballers

Saber-Ayad

Nassar

Latif

2013

J Renin Angiotensin Aldosterone Syst

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Background: The renin-angiotensin-aldosterone system plays a role in physiological and pathological responses of the heart to both static and dynamic exercise. Previous studies showed that the level of angiotensin II is determined by the angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism. Aim: We aimed in this study to determine the effect of ACE I/D gene polymorphism on the extent of functional and structural cardiac changes in response to one year of professional football training in young footballers. Methods and results:We studied 68 young male football players and a comparable control group. Besides medical history and clinical examination, 12 lead ECG and transthoracic 2D echocardiography examination were performed. Genotyping of ACE was analyzed using PCR-based technique. There was no statistically significant difference in distribution of genotypes among athletes compared with control subjects. D allele showed a graded effect on both EF (73.55, 67.5 and 60.2%, p=0.03) and PASP (37.6, 26.1 and 21.39 mmHg, p=0.02) in DD, ID and II subjects, respectively. Conclusion: Early cardiac changes in young footballers can be affected by ACE I/D polymorphism. There is a summative effect of the D allele in increasing EF and PASP in response to professional football training.

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Ultrasonographic study of left ventricular function at rest in a group of highly trained black African handball players

Cited by 20 publications

References 21 publications

A Meta-Analysis of Aortic Root Size in Elite Athletes

A Meta-Analysis of Aortic Root Size in Elite Athletes

Hypertensive heart disease in Africa

Angiotensin-converting enzyme I/D gene polymorphism affects early cardiac response to professional training in young footballers

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