“…Given the wide variety of diseases that can be encountered, advanced imaging modalities play a major role in the diagnostic and staging assessment of the lesion, guiding therapeutic decisions and monitoring or follow-up of treatment (Penninck et al, 2001;Collins et al, 2013). CT, MRI (Boroffka and Voorhout, 1999;Armour et al, 2011;Lederer et al, 2015) and ultrasound (US) have been demonstrated to be accurate in evaluating orbital disease (Mason et al, 2001;Boroffka et al, 2007). In addition, US has been demonstrated to be particularly useful in guiding interventional procedures throughout the body both in veterinary and in human patients (Phillips and Schneider, 1981;Gupta et al, 1999;Constantin et al, 2010;Orlandi et al, 2013;Spiess and Pot, 2013).…”