Ultrasonographic features of intravascular fasciitis: case report and review of the literature

Takahashi, Kanae; Yanagi, Teruki; Imafuku, Kimiaki; Kitamura, Shinya; Inamura-Takashima, Y.; Yamaguchi, Yasutaka; Hata, Hiroo; Shimizu, Hiroshi

doi:10.1111/jdv.14293

Cited by 8 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The size of the lesions range from 0.6 to 5 cm, and the course of the disease was 2 weeks−8 years ( 16 ). Other features manifested as with or without pain/tenderness, slow growing, mobility, and regional discomfort ( 20 ). Cases affecting the large veins often present symptoms of venous thrombosis.…”

Section: Discussionmentioning

confidence: 99%

Intravascular Fasciitis of the Jugular Vein Mimicking Thrombosis and Sarcoma: A Case Report

Chen

Wen

et al. 2021

Front. Surg.

View full text Add to dashboard Cite

Background: Intravascular fasciitis is a rare disease that is a reactive proliferative lesion of myofibroblasts. There are rare reports that intravascular fasciitis has invaded the jugular vein as seen in this case.Case Presentation: A 41-year-old female presented with right neck dull pain for 20 days. The appearance of the subcutaneous mass was oval, pink hyaline, well-demarcated, and measuring ~5 mm in diameter. Microscopically, the mass was composed of spindle cells arranged in intersecting fascicles. Immunohistochemical stains showed that the spindle cells were positive for smooth muscle actin and negative for S-100, Desmin, MyoD1, and elastin stains. The nuclei of the spindle cells were relatively uniform, and mitotic activity was observed. The overall morphological and immunohistochemical features are consistent with intravascular fasciitis.Conclusion: Due to the rapid growth and vascular invasion, intravascular fasciitis created a high risk of misdiagnosing it as a sarcoma or thrombosis. Reporting this uncommon case, we raise awareness of this non-neoplastic lesion, and careful, light microscopic examination combined with immunohistochemical staining aids in the diagnosis of intravascular fasciitis.

show abstract

Section: Discussionmentioning

confidence: 99%

Intravascular Fasciitis of the Jugular Vein Mimicking Thrombosis and Sarcoma: A Case Report

Chen

Wen

et al. 2021

Front. Surg.

View full text Add to dashboard Cite

show abstract

“…The histology of IVF is very similar to that of typical nodular fasciitis, but it often involves the layers and lumens of blood vessels, frequently leading to an overdiagnosis of vascularized malignancies[ 2 , 3 ]. IVF most commonly occurs in the upper extremities, head and neck, followed by the lower extremities and trunk, but there have been reports of rare sites, such as the mouth and maxillofacial region[ 4 - 7 ]. This study reports intravascular nodular fasciitis of the external jugular vein and subclavian vein and explores its clinical and pathological features, diagnosis and differential diagnosis combined with a literature review to raise awareness of rare lesions and avoid misdiagnosis.…”

Section: Introductionmentioning

confidence: 99%

Intravascular fasciitis involving the external jugular vein and subclavian vein: A case report

Meng¹,

Liu²,

Xie³

et al. 2022

WJCC

View full text Add to dashboard Cite

BACKGROUND Intravascular fasciitis (IVF) is a rare nodular fasciitis that often involves the layers and lumens of blood vessels; therefore, it is easily misdiagnosed as a malignant tumor with invasion into blood vessels. CASE SUMMARY A 13-year-old boy was admitted due to a mass on the left side of his neck. Duplex ultrasonography revealed a circular solid hypoechoic mass in the external jugular vein, and magnetic resonance imaging revealed an enhanced longitudinal mass-like lesion in the left supraclavicular fossa. Surgical treatment was arranged and completed, histopathological analysis showed a large amount of spindle cell proliferation, and immunohistochemistry showed that the spindle cells were positive for the expression of vimentin, caldesmon, and smooth muscle actin and negative for the expression of S-100 protein, desmin, CD34, and c-kit; Ki-67 staining revealed a low proliferative index (5%-10%), which confirmed the differentiation characteristics of myofibroblasts. Fluorescence in situ hybridization detected the rearrangement of USP6. IVF was subsequently diagnosed. CONCLUSION IVF is characterized by intraluminal, intramural and extramural involvement of small to large arteries or veins. Unless the doctor has a deep understanding of the disease or suspects that there is an initial indicator, IVF may be confused with other intravascular malignancies, leading to unnecessary radical surgery. Imaging examination combined with histopathological examination can improve the diagnostic accuracy of this disease.

show abstract

“…1,5,14 It usually develops as a rapidly growing painless mass that can be made symptomatic by obstructing the lumen of the blood vessel during its growth. 5,15 IF can originate from small intradermal vessels to large caliber veins. It has been described in arteries and veins of trunk and limbs (digital artery, palmar vein arch, anterior tibial vein, femoral vein) as well as in head and neck vessels, orbit and submucosa of the oral cavity.…”

mentioning

confidence: 99%

“…5 Ultrasonography may aid in the diagnosis of soft tissue lesions but the combination of CT and MRI has been shown to be more useful. 5,15 Differential diagnosis of retroperitoneal lesions should be made with other malignant neoplastic processes such as spindle cell carcinoma (positive for cytokeratins AE1 / AE3), melanoma metastases (positive for S-100 protein), gastrointestinal mesenchymal stromal tumors GIST) positive for CD117, solitary fibrous tumor (positive for CD34), liposarcomas, leiomyosarcomas, rhabdomyosarcomas, Edwin's sarcoma, epithelial angiosarcomas (positive for CD34 and CD31) as well as with peritoneal implants suggestive of peritoneal carcinomatosis. Other benign processes such as fibromatosis (positive for beta-catenin), pyogenic granuloma, hamartomatosis, adventitious periquistic disease, hemangioendotheliomas, leiomyomas, myofibroblastic tumor (Alk-1 positive) or Masson's tumor.…”

mentioning

confidence: 99%

“…Other benign processes such as fibromatosis (positive for beta-catenin), pyogenic granuloma, hamartomatosis, adventitious periquistic disease, hemangioendotheliomas, leiomyomas, myofibroblastic tumor (Alk-1 positive) or Masson's tumor. 5,14,15,[17][18][19] Fine needle aspiration (FNA) of the lesion, as in cases of PF, may be an acceptable method for diagnosis, although the gold standard is the surgical excision of the lesion on suspicion of malignancy, thus avoiding the possibility of local dissemination during the procedure. 20,21 Some authors propose follow-up of the lesion, based on histology and as long as malignancy has been ruled out.…”

mentioning

confidence: 99%

See 1 more Smart Citation

What do we know about intravascular fasciitis affecting inferior vena cava? management and report of a case

et al. 2017

View full text Add to dashboard Cite

Intravascular fasciitis is a rare entity characterized by the proliferation of myofibroblasts and giant cells in relation to small and medium-sized blood vessels. It characterized by a rapid growth and its morphology can simulate other malignant neoplastic processes of more aggressive behavior such as sarcomas. It belongs to a group of benign lesions that affect the subcutaneous tissue and fascia (sometimes to the muscle) sharing characteristics similar to proliferative fasciitis, nodular fasciitis and proliferative myositis. It can sometimes be confused with lesions typical of fibromatosis even. We report a case of a patient with a symptomatic retroperitoneal mass who underwent surgery. The intraoperative findings showed a tumor originating in the inferior vena cava. The histopathological study revealed an intravascular fasciitis.

show abstract

Ultrasonographic features of intravascular fasciitis: case report and review of the literature

Cited by 8 publications

References 6 publications

Intravascular Fasciitis of the Jugular Vein Mimicking Thrombosis and Sarcoma: A Case Report

Intravascular Fasciitis of the Jugular Vein Mimicking Thrombosis and Sarcoma: A Case Report

Intravascular fasciitis involving the external jugular vein and subclavian vein: A case report

What do we know about intravascular fasciitis affecting inferior vena cava? management and report of a case

Contact Info

Product

Resources

About