Ultrasonographic evaluation of superficial lymph node metastases in melanoma

Tregnaghi, Alberto; Candia, Alessandro De; Calderone, Milena; Cellini, Lisa; Róssi, Carlo; Talenti, Enrico; Blandamura, Stella; Borsato, Simonetta; Muzzio, Pier Carlo; Rubaltelli, Léopoldo

doi:10.1016/s0720-048x(96)01102-3

Cited by 62 publications

(41 citation statements)

References 21 publications

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“…Sonography of the lymph nodes was the most efficient technical method to detect relapses (range: 10 -16%) in all phases of followup. This is in line with recent reports suggesting that lymph nodes sonography improves early detection of locoregional metastases (Tregnaghi et al, 1997;Blum et al, 2000). The efficiency-costs ratio in our study was best at initial staging and the follow-up in stage III.…”

Section: Cost Efficiency/patients Survivalsupporting

confidence: 93%

Primary staging and follow-up in melanoma patients – monocenter evaluation of methods, costs and patient survival

et al. 2002

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In a German cohort of 661 melanoma patients the performance, costs and survival benefits of staging methods (history and physical examination; chest X-ray; ultrasonography of the abdomen; high resolution sonography of the peripheral lymph nodes) were assessed at initial staging and during follow-up of stage I/II+III disease. At initial staging, 74% (23 out of 31) of synchronous metastases were first detected by physical examination followed by sonography of the lymph nodes revealing 16% (5 out of 31). Other imaging methods were less efficient (Chest X-ray: one out of 31; sonography of abdomen: two out of 31). Nearly 24% of all 127 first recurrences and 18% of 73 second recurrences developed in patients not participating in the follow-up programme. In follow-up patients detection of first or second recurrence were attributed to history and physical examination on a routine visit in 47 and 52% recurrences, respectively, and to routine imaging procedures in 21 and 17% of cases, respectively. Lymph node sonography was the most successful technical staging procedure indicating 13% of first relapses, but comprised 24% of total costs of follow-up in stage I/II. Routine imaging comprised nearly 50% of total costs for follow-up in stage I/II and in stage III. The mode of detecting a relapse ('patient vs. doctor-diagnosed' or 'symptomatic vs asymptomatic') did not significantly influence patients overall survival. Taken together, imaging procedures for routine followup in stage I/II and stage III melanoma patients were inefficient and not cost-efficient.

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Section: Cost Efficiency/patients Survivalsupporting

confidence: 93%

Primary staging and follow-up in melanoma patients – monocenter evaluation of methods, costs and patient survival

et al. 2002

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“…A circular/ oval hypoechoic lymph node with a Solbiati index less than 1.5 and no hyperechoic hilum constituted the major criteria for metastatic involvement. Minor criteria for nodal metastasis were a nodular hypoechoic focus within a lymph node with an irregular lymph node margin, 20 and stringent criteria were the presence of all 3 major criteria ( Figure 1). Nonstringent criteria of nodal metastasis were the presence of 1 or 2 major criteria and/or 1 or 2 minor criteria (Figure 2).…”

Section: Palpation and Ultrasonographymentioning

confidence: 99%

“…Minor criteria for nodal metastasis were nodular hypoechoic focus within a lymph node and irregularity of lymph node margin. 20 Stringent criteria for metastatic nodes were the presence of all 3 major criteria. Nonstringent criteria of nodal metastasis were the presence of 1 or 2 major criteria and/or 1 or 2 minor criteria.…”

Section: Commentmentioning

confidence: 99%

Ultrasonography Using Simple Diagnostic Criteria vs Palpation for the Detection of Regional Lymph Node Metastases of Melanoma

Saïag¹,

Bernard²,

Beauchet³

et al. 2005

Arch Dermatol

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“…62 Several methods have been reported regarding the discrimination of malignant lymph nodes with conventional US but the outcome seems not satisfactory enough. 63 Experimental studies demonstrated potential benefits of usage of US related contrasts in SLN detection. 64,65 Contrast enhanced ultrasound (CEUS) agents are composed of a dispersion of microbubbles (each is smaller than a red blood cell) that act as reflectors of the ultrasound beam.…”

Section: 54mentioning

confidence: 97%

A Review of Techniques for Sentinel Lymph Node Mapping with Special Reference to the Head and Neck Region

Sun¹

2016

ICPJL

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Sentinel lymph node biopsy is an extensively explored diagnostic mean for reducing surgical risks while improving staging in different human malignancies. Several different techniques have been introduced to clinical use during last two decades. Methods as ink lymphography and lymphoscintigraphy have already established their position in sentinel nodes mapping. Novel approaches as CT, MRI-lymphography, contrast enhanced ultrasound and near-infrared fluorescence imaging possesses prominent potential advantages and demand further experience gaining. A review of the clinically utilized techniques is presented a special attention is drawn to their usefulness in the head and neck carcinomas work-up. Keywords

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Ultrasonographic evaluation of superficial lymph node metastases in melanoma

Cited by 62 publications

References 21 publications

Primary staging and follow-up in melanoma patients – monocenter evaluation of methods, costs and patient survival

Primary staging and follow-up in melanoma patients – monocenter evaluation of methods, costs and patient survival

Ultrasonography Using Simple Diagnostic Criteria vs Palpation for the Detection of Regional Lymph Node Metastases of Melanoma

A Review of Techniques for Sentinel Lymph Node Mapping with Special Reference to the Head and Neck Region

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