Ultrasonographic diaphragm thickness correlates with compound muscle action potential amplitude and forced vital capacity

Noda, Yasuo; Sekiguchi, Kenji; Kohara, Nobuo; Kanda, Fumio; Toda, Tatsushi

doi:10.1002/mus.24902

Cited by 58 publications

(41 citation statements)

References 33 publications

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“…Detection of diaphragm dysfunction by US over the chest wall can be performed at the bedside. 8 In our patient, mild abnormalities were found on single-fiber EMG without a decremental response during repetitive nerve stimulation, suggesting minor neuromuscular junction dysfunction, likely too mild for significant respiratory muscle weakness to be present from myasthenia gravis. Clinical findings, fibrillation potentials of the diaphragm on EMG, and a thin diaphragm on US support a myopathic process as the major factor causing respiratory failure in this patient.…”

Section: Discussionmentioning

confidence: 50%

“…Fibrillation potentials on needle EMG of the diaphragm can prove active muscle damage, but there is a risk of pneumothorax. Detection of diaphragm dysfunction by US over the chest wall can be performed at the bedside . In our patient, mild abnormalities were found on single‐fiber EMG without a decremental response during repetitive nerve stimulation, suggesting minor neuromuscular junction dysfunction, likely too mild for significant respiratory muscle weakness to be present from myasthenia gravis.…”

Section: Discussionmentioning

confidence: 69%

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Diaphragm involvement in immune checkpoint inhibitor‐related myositis

et al. 2019

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 69%

Diaphragm involvement in immune checkpoint inhibitor‐related myositis

et al. 2019

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“…Although CMAP amplitude is utilized in assessing the degree of innervation, CMAP duration and latency have clinical value in evaluating nerve conduction and myelination. These two CMAP measures are somewhat related because they are principally affected by the speed of axonal signal propagation.…”

Section: Discussionmentioning

confidence: 99%

“…Successful transcutaneous stimulation of the RLN will likely require detailed anatomical understanding of the course of the nerve, 25 with the possible assistance of ultrasound. 26 Although CMAP amplitude is utilized in assessing the degree of innervation, [27][28][29] CMAP duration and latency have clinical value in evaluating nerve conduction and myelination. These two CMAP measures are somewhat related because they are principally affected by the speed of axonal signal propagation.…”

Section: Discussionmentioning

confidence: 99%

Compound motor action potential duration and latency are markers of recurrent laryngeal nerve injury

et al. 2017

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“…-Grosor diafragmático: El grosor del diafragma depende de la masa muscular y esta se correlaciona con la capacidad vital forzada 73 . La disminución del grosor diafragmático se asocia al descenso de amplitud valorada por electromiografía y puede indicar la presencia de atrofia 23, 74 .…”

Section: Ultrasonografíaunclassified

Disfunción diafragmática: una realidad en el paciente ventilado mecánicamente

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2017

Archivos de Bronconeumología

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3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 1 ResumenLa afectación muscular del paciente crítico está presente en la mayoría de pacientes que ingresan en el Servicio de Medicina Intensiva (SMI). La alteración, en particular, del músculo diafragmático, inicialmente englobada en esta categoría, se ha diferenciado en los últimos años y se ha demostrado la existencia de una disfunción muscular propia de los pacientes sometidos a ventilación mecánica. En este subgrupo de pacientes, encontramos una disfunción muscular que aparece de manera precoz después del inicio de la ventilación mecánica y que se relaciona, principalmente, con el uso de modalidades control, la presencia de sepsis y/o de fracaso multiorgánico. Aunque se desconoce la etiología concreta que desencadena el proceso, el músculo presenta procesos de estrés oxidativo y alteración mitocondrial, que provocan un desequilibrio en la síntesis proteica, con el resultado de atrofia y alteración de la contractilidad y, como consecuencia, una menor funcionalidad. No fue, de hecho, hasta 2004 cuando Vassilakopoulos et al describieron el término "Disfunción diafragmática asociada a ventilación mecánica" que junto a la lesión por sobre distensión pulmonar y por barotrauma, representan un reto en el día a día de los pacientes ventilados.La disfunción diafragmática tiene influencia en el pronóstico, retardando la extubación, aumentando la estancia hospitalaria y afectando la calidad de vida de estos pacientes en los años siguientes al alta hospitalaria. La ecografía, como técnica no invasiva y accesible en la mayoría de Unidades, podría ser de utilidad en el diagnóstico precoz para iniciar, de forma avanzada, la rehabilitación e influir positivamente en el pronóstico de estos enfermos.Palabras clave: Diafragma, disfunción diafragmática, ventilación mecánica, ecografía. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 2 *Manuscrito (sin información de autores) AbstractThe critical patient muscle involvement is present in most patients admitted to the intensive care unit (ICU). Specifically the diaphragmatic muscle alteration, initially considered in this category, has been differentiated in recent years, and it has been demonstrated the existence of this muscular dysfunction during mechanical ventilation. In this subgroup of patients, we found that this muscle dysfunction appears at an early stage after the start of mechanical ventilation, which is mainly related to the use of modalities control, and also in presence of sepsis and/or multi-organ failure. Although the specific etiology that triggers the processes unknown, the muscle has processes oxidative stress and mitochond...

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Ultrasonographic diaphragm thickness correlates with compound muscle action potential amplitude and forced vital capacity

Abstract: Diaphragm USG is useful for objective evaluation of pulmonary function in neuromuscular disorders without requiring undue patient effort or cooperation.

Cited by 58 publications

References 33 publications

Diaphragm involvement in immune checkpoint inhibitor‐related myositis

Diaphragm involvement in immune checkpoint inhibitor‐related myositis

Compound motor action potential duration and latency are markers of recurrent laryngeal nerve injury

Disfunción diafragmática: una realidad en el paciente ventilado mecánicamente

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