“…1 The spectrum of findings seen with amniotic band syndrome is principally determined by the gestational age at which entanglement occurs, with a date of insult typically ranging from 6 to 18 weeks' gestation. 1,2 Although the underlying cause of amniotic bands remains unclear, affected fetuses share similar disruption pathways, typically showing a broad range of manifestations. Common findings include constriction rings around the digits, lymphedema distal to the level of band constriction, amputation of extremities or digits, clubfeet, clubhands, multiple joint contractures, chest or abdominal wall defects, microphthalmos, ocular abnormalities, and facial clefts.…”