Ultrasonic Manifestations of Mesenteric Inflammatory Myofibroblastic Tumors in Children

Abstract

Objective: To explore the ultrasonic manifestations of mesenteric inflammatory myofibroblastic tumors (IMTs) in children.Methods: Seven patients with mesenteric IMTs were retrospectively analyzed. The ultrasonic manifestations, such as the locations, sizes, morphology, borders, internal echo, blood flow, and metastasis, of the tumors were detected.Results: In all the seven pediatric patients, a solitary lesion was found for the mesenteric IMTs, including five cases in the ileocecal mesentery and two cases in the mesentery of ascending colon. All the single tumors were revealed as irregular hypoechoic masses with uneven internal echoes and enhanced echoes in the surrounding intestine and omentum. Internal blood flow signals were enriched in the tumors. The borders were clear in five cases and unclear in two cases. In addition, two cases had peritoneal effusion and one case had calcified plaques. In the follow-up studies, one of the seven IMT patients had malignant transformation, and one case was transferred to the pelvic cavity.Conclusion: Ultrasonic examination can clearly demonstrate the locations, sizes, morphology, borders, internal echo, blood flow as well as metastasis of the pediatric IMT of the mesentery, having an important clinical application value as an adjunct to computed tomography (CT).

Recurrent infantile inflammatory myofibroblastic tumor of mesentery––Case report and review of imaging findings

“…At US, IMT typically appears as an ill- or well-defined, heterogeneous, solid, hypo- or hyperechoic mass. A recent case series of US findings of mesenteric IMT described them as irregular hypoechoic masses in all cases with vascularity similar to our patient [14] . The margins can be well defined or ill defined, but usually infiltration to surrounding structures is lacking due to borderline malignant nature of these lesions.…”

“…The margins can be well defined or ill defined, but usually infiltration to surrounding structures is lacking due to borderline malignant nature of these lesions. Frankly malignant IMT can have infiltrative features, though they are uncommon [14] . All the cases described in above case series were solitary similar to our case and is consistent with previous literature [5 , 14] .…”

Anaplastic Lymphoma Kinase Positive Mesenteric Inflammatory Myofibroblastic Tumor in Adult Woman

“…Larger tumors may show central necrosis or calcification [ 13 ]. Mesenteric IMTs on ultrasound have been described as well-defined or ill-defined, heterogeneous, hypoechoic, or hyperechoic solid masses with internal complexity and vascularity [ 15 , 16 ]. On MR imaging, IMTs are typically T1-hypointense and T2-hypointense with variable internal T1 and T2-hypointense fibrotic stroma with heterogeneous gadolinium enhancement [ 12 , 16 ].…”

Ultrasound and computed tomography in the evaluation of mesenteric lesions: A pictorial review

“…The aim of this article is to describe the spectrum of imaging findings of the various mesenteric lesions using ultrasound and CT. echogenicity in the surrounding mesentery and omentum on USG and show increased internal vascularity on colour Doppler. 3 Inflammatory myofibroblastic tumour appears as a hypo or iso-attenuating mass compared with skeletal muscle depending on the amount of myxoid or collagenous stroma, respectively. Dense central calcification may be noticed.…”