Ultrasonic-Frequency-Based Visualization of Columnar Soft Matter Beyond Wavelength Limitations

Hata, Yutaka; Takashima, Yuya; Tsukuda, Koki; Kikuchi, Sho; Ishikawa, Tomomoto

doi:10.1109/tsmc.2016.2598294

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…On the contrary, the current study investigated the reflected backscattered ultrasound. In addition, broadband ultrasound single-probe testing reveals an inverse relationship between the frequency and diameter of the columnar soft matter, 31 which suggests that a lower frequency of the reflected backscattered waveform was observed for the softer lines. Moreover, the cross-spectrum analysis used herein is a standard method for determining the relationship between two time-series as a function of frequency.…”

Section: Nicholson Et Al Observed the Bone Healing Process Of Clavicl...mentioning

confidence: 99%

Ultrasound Frequency-Based Monitoring for Bone Healing

Kumabe

Morimoto

et al. 2021

Tissue Engineering Part C: Methods

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Correct assessment of the bone healing process is required for the management of limb immobilization during the treatment of bone injuries, including fractures and defects. Although the monitoring of bone healing using ultrasound poses several advantages regarding cost and ionizing radiation exposure compared with other dominant imaging methods, such as radiography and CT, traditional ultrasound B-mode imaging lacks reliability and objectivity. However, the body structures can be quantitatively observed by ultrasound frequency-based methods, and therefore, the disadvantages of B-mode imaging can be overcome. In this study, we created a femoral bone hole model of a rat and observed the bone healing process using the quantitative ultrasound method and micro-CT, which provides a reliable assessment of the tissue microstructure of the bone. The current study analyzed the correlation between these two assessments. The results revealed that the quantitative ultrasound measurements correlated with the CT measurements for rat bone healing. This ultrasound frequency-based method could have the potential to serve as a novel modality for quantitative monitoring of bone healing with the advantages of being less invasive and easily accessible. Impact statementBone healing monitoring with ultrasound is advantageous as it is less invasive and easily accessible; however, the traditional B-mode method lacks reliability and objectivity. This study demonstrated that the proposed ultrasound frequency-based monitoring method can quantitatively observe bone healing and strongly correlates with the CT measurements for rat bone healing. This method has the potential to become a reliable modality for monitoring bone healing.

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Section: Nicholson Et Al Observed the Bone Healing Process Of Clavicl...mentioning

confidence: 99%