Ultrasonic Diagnosis and Treatment of Tumors Using Multifunctional Hollow Mesoporous Silicon Nanoparticles
Jiawei Zhang,
Tiantian Guo,
Kunlun Liu
et al.
Abstract:In recent years, the application of hollow mesoporous silicon nanoparticles in the biomedical field has attracted much attention because of their excellent features. In this study, the sonosensitizer curcumin (Cur), the chemotherapy drug doxorubicin (Dox), and the perfluoropropane (C 3 F 8 ) gas were loaded into a multifunctional hollow mesoporous silica nanoparticle (MHMSN). The surface of MHMSN was modified with a biotin molecule and acid-sensitive groups (cis-aconitic anhydridepolyethylene glycol, CDM-PEG).… Show more
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