Ultrasonic Detection of Middle Ear Effusion

Discolo, Christopher M.; Byrd, Michael C.; Bates, Teresa A.; Hazony, D.; Lewandowski, Jan; Koltai, Peter J.

doi:10.1001/archotol.130.12.1407

Cited by 18 publications

(11 citation statements)

References 10 publications

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“…Discolo et al recently evaluated the efficacy of ultrasound in detecting middle ear effusion in children and found it to be accurate and able to distinguish thin from mucoid fluid [19]. Chianese et al compared spectral gradient acoustic reflectometry to tympanometry in children aged 6-24 months and found it less accurate than tympanometry [20].…”

Section: Discussionmentioning

confidence: 99%

Prospective comparison of handheld pneumatic otoscopy, binocular microscopy, and tympanometry in identifying middle ear effusions in children

Rogers

Boseley

Adams

et al. 2010

International Journal of Pediatric Otorhinolaryngology

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Section: Discussionmentioning

confidence: 99%

Prospective comparison of handheld pneumatic otoscopy, binocular microscopy, and tympanometry in identifying middle ear effusions in children

Rogers

Boseley

Adams

et al. 2010

International Journal of Pediatric Otorhinolaryngology

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“…In continuation of our previous study, 9 this study aims to highlight the use of a computerized interpretation of the produced ultrasound waveform of the middle ear. This advances progress to create a non-invasive handheld ultrasound device that may assist the physician to interpret the middle ear contents with higher confidence and accuracy than tympanometry and pneumotoscopy.…”

Section: Discussionmentioning

confidence: 99%

“…[7][8] Most recently Discolo et al 9 from our institution used a single propagating wave A-mode ultrasound in a preliminary group of patients. The waveforms produced were interpreted by a single human interpreter.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound Characterization of Middle Ear Effusion

Seth¹,

Discolo²,

Krakovitz³

2008

Otolaryngol.--head neck surg.

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Purpose-To further enhance and assess the ability to characterize middle ear effusion (MEE) using non-invasive ultrasound technology.Materials and Methods-This is a prospective unblinded comparison study. Fifty-six children between the ages of 6 months and 17 years scheduled to undergo bilateral myringotomy with pressure equalization tube placement were enrolled. With the child anesthetized, the probe was placed into the external ear canal after sterile water was inserted. Ultrasound recordings of middle ear contents were analyzed by computer algorithm. Middle ear fluid was collected during myringotomy and analyzed for bacterial culture and viscosity.Results-Ultrasound waveforms yielded a computer algorithm interpretation of middle ear contents in 66% of ears tested. When a result was obtained, the sensitivity and specificity for successfully characterizing middle ear fluid content as either void of fluid, thick fluid (mucoid), or thin fluid (serous or purulent) was at least 94%. Mucoid effusions had higher measured viscosity values (P=0.002). Viscosity measures were compared to culture result, and those with low viscosity (thin consistency) had a higher likelihood of having a positive culture (P=0.048). Conclusion-The device sensitivity and specificity for fluid detection was 94% or greater among interpretable waveforms (66% of those tested). Although this technology provides important information of the middle ear effusion presence and characteristic, further technological improvements are needed.

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“…Tympanocentesis, the removal of a MEE by aspiration through a needle, can be performed to remove and directly examine a MEE[12], but it is rarely performed in most primary care clinics as it is considered an invasive procedure that carries additional risk to the patient. Ultrasound-based methods for assessing for the presence of a MEE have excellent accuracy [13], but lack the ability to spatially resolve middle ear biofilms, and typically require unobstructed water-based coupling through the outer ear canal. As a result, there is an unmet need for a technique in the clinician’s toolbox that can visually identify and quantitatively characterize a MEE, as well as assess the middle ear for infection noninvasively and in vivo .…”

Section: Introductionmentioning

confidence: 99%

Non‐invasive optical assessment of viscosity of middle ear effusions in otitis media

Monroy

Pande²,

Shelton

et al. 2016

Journal of Biophotonics

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Eustachian tube dysfunction can cause fluid to collect within the middle ear cavity and form a middle ear effusion (MEE). MEEs can persist for weeks or months and cause hearing loss as well as speech and learning delays in young children. The ability of a physician to accurately identify and characterize the middle ear for signs of fluid and/or infection is crucial to provide the most appropriate treatment for the patient. Currently, middle ear infections are assessed with otoscopy, which provides limited and only qualitative diagnostic information. In this study, we propose a method utilizing cross-sectional depth-resolved optical coherence tomography to noninvasively measure the diffusion coefficient and viscosity of colloid suspensions, such as a MEE. Experimental validation of the proposed technique on simulated MEE phantoms with varying viscosity and particulate characteristics is presented, along with some preliminary results from in vivo and ex vivo samples of human MEEs.

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Ultrasonic Detection of Middle Ear Effusion

Abstract: To assess the ability to detect and characterize middle ear effusion in children using A-mode ultrasonography.

Cited by 18 publications

References 10 publications

Prospective comparison of handheld pneumatic otoscopy, binocular microscopy, and tympanometry in identifying middle ear effusions in children

Prospective comparison of handheld pneumatic otoscopy, binocular microscopy, and tympanometry in identifying middle ear effusions in children

Ultrasound Characterization of Middle Ear Effusion

Non‐invasive optical assessment of viscosity of middle ear effusions in otitis media

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