Ultrasmall iron-doped zinc oxide nanoparticles for ferroptosis assisted sono-chemodynamic cancer therapy

Yu, Jing; Zhu, Fangyin; Yang, Ya; Zhang, Peixia; Zheng, Yilin; Chen, Haijun; Gao, Yu

doi:10.1016/j.colsurfb.2023.113606

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Ferroptosis Inducers2

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2024

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Cited by 3 publications

(2 citation statements)

References 48 publications

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“…Nanomaterials are increasingly being investigated for their role in inducing ferroptosis due to their biocompatibility, nano effect, and permeability 234 ( Table 2 ).…”

Section: Ferroptosis Inducersmentioning

confidence: 99%

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Ferroptosis in Cancer Therapy: Mechanisms, Small Molecule Inducers, and Novel Approaches

Luo,

Bai,

Zhang

et al. 2024

DDDT

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“…Nanomaterials are increasingly being investigated for their role in inducing ferroptosis due to their biocompatibility, nano effect, and permeability 234 ( Table 2 ).…”

Section: Ferroptosis Inducersmentioning

confidence: 99%

“…When combined with ultrasonic energy, FZO-ASP showed enhanced inhibition of cancer cell proliferation and mouse mammary tumor growth, with no significant toxicity observed in treated mice. 234 …”

Section: Ferroptosis-inducing Therapy In Pdt and Sdtmentioning

confidence: 99%

Ferroptosis in Cancer Therapy: Mechanisms, Small Molecule Inducers, and Novel Approaches

Luo,

Bai,

Zhang

et al. 2024

DDDT

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Understanding the Novel Approach of Nanoferroptosis for Cancer Therapy

Sheikh,

Kesharwani,

Almalki

et al. 2024

Nano-Micro Lett.

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As a new form of regulated cell death, ferroptosis has unraveled the unsolicited theory of intrinsic apoptosis resistance by cancer cells. The molecular mechanism of ferroptosis depends on the induction of oxidative stress through excessive reactive oxygen species accumulation and glutathione depletion to damage the structural integrity of cells. Due to their high loading and structural tunability, nanocarriers can escort the delivery of ferro-therapeutics to the desired site through enhanced permeation or retention effect or by active targeting. This review shed light on the necessity of iron in cancer cell growth and the fascinating features of ferroptosis in regulating the cell cycle and metastasis. Additionally, we discussed the effect of ferroptosis-mediated therapy using nanoplatforms and their chemical basis in overcoming the barriers to cancer therapy.

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Synthesis, characterization and antibacterial mechanism study of small water-soluble iron-doped zinc oxide nanoparticles

Sun,

Yu,

et al. 2024

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Ultrasmall iron-doped zinc oxide nanoparticles for ferroptosis assisted sono-chemodynamic cancer therapy

Cited by 3 publications

References 48 publications

Ferroptosis in Cancer Therapy: Mechanisms, Small Molecule Inducers, and Novel Approaches

Ferroptosis in Cancer Therapy: Mechanisms, Small Molecule Inducers, and Novel Approaches

Understanding the Novel Approach of Nanoferroptosis for Cancer Therapy

Synthesis, characterization and antibacterial mechanism study of small water-soluble iron-doped zinc oxide nanoparticles

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