“…Acetone, one of the most toxic and irritating volatile organic gases, can cause coma and vomiting in the human body when it is inhaled at a level above 173 ppm. Moreover, long-term exposure to high-concentration acetone will lead to central nervous system anesthesia and liver damage. , Medical studies have shown that acetone can be a marker of the exhaled gas of diabetes since the concentration of exhaled acetone would be as high as 1.8 ppm for diabetic patients but is well around 300–900 ppb for healthy people. , The accurate detection of acetone concentration is one of the most important auxiliary methods for both medical diagnosis and air quality control. The conventional ways of detecting acetone gas, such as gas chromatography, Raman spectroscopy, and electrochemical methods, have the disadvantages of large instruments, high cost, and inconvenient operation. − Nevertheless, metal oxide semiconductor (MOS) sensors based on ZnO, SnO 2 , WO 3 , In 2 O 3 , etc., provide an effective platform with small size, high sensitivity, and easy operation for detecting acetone gas. − Hence, designing an acetone analyzer based on MOS nanomaterials with superior selective sensing performances typically at a low concentration under high relative humidity is significantly attractive in the field of sensors.…”