Ultrasensitive electrochemiluminescence immunosensor based on luminol functionalized gold nanoparticle labeling

Enhanced electrochemiluminescence from luminol at multi-walled carbon nanotubes decorated with palladium nanoparticles: A novel route for the fabrication of an oxygen sensor and a glucose biosensor

“…The ECL signal intensity at the fixed concentration of oxygen (0.29 mM) was linear with the concentration of luminol in the range between 50 nM and 100 M (r = 0.9997). The sensitive determination of luminol is necessary for some immunological determinations [28,29,48]. Also, the ECL signal intensity of luminol (100 M) was linear with the concentration of dissolved oxygen in the range between 0.08 and 0.94 mM (r = 0.9996).…”

“…The sensitized luminol ECL reactions have been applied for the detection of superoxide dismutase (SOD) based on the quenching effect of SOD on luminol-O 2 ECL system by scavenging reactive oxygen species, for the detection of horseradish peroxidase (HRP) based on its enhancing effect on luminol-O 2 ECL reaction [12], and for the indirect determination of glucose [11,13,14,27] and choline [26] which react with their related enzymes and produce hydrogen peroxide. The sensitized ECL reactions make a possibility for sensitive, simple and inexpensive measurement of dissolved O 2 in the environmental, biomedical and luminol target immunological reactions [12,[28][29][30]. Recently, a novel and robust oxygen gas sensor has been presented by Zhang et al [31] based on electrochemiluminescence of Ru(bpy) 3 3+/+ ion annihilation in an ionic liquid medium.…”

Surface Modification of Superparamagnetic Magnetite Nanoparticles and Its Application for Detection of Anti-CEA Using Electrochemiluminescent Immunosensor

“…The ECLIA is a new generation immunolabelling technique with the advantages of magnetic beads, immunoassay, and ECL [37,38]. On the basis of these outstanding advantages, ECLIA technique has been widely used in immunoassay, cell separation, DNA, and drug delivery systems [39][40][41][42][43][44][45][46][47].…”

The development of an electrochemical immunosensor using a thiol aromatic aldehyde and PAMAM-functionalized Fe3O4@Au nanoparticles

“…Nanomaterials, including gold nanoparticles [8,9], carbon nanotubes [10], and complexes of some nanomaterials [11,12], were used as carriers for immobilizing secondary antibodies labeled with enzymes, which allowed the attachment of multiple enzyme bioconjugations. Recently, Fe 3 O 4 @Au nanoparticles were also used to improve the sensitivity of the immunosensor owing to their good stability, extremely high surface-to-volume ratio and biocompatibility, and much higher catalytic activity [13][14][15].…”