Ultrasensitive detection of NSE employing a novel electrochemical immunosensor based on a conjugated copolymer

Abstract

The current study designed and tested a simple and highly specific label-free impedimetric neuron specific enolase (NSE) immunosensor based on a copolymer matrix-coated disposable electrode. The copolymer matrix was prepared...

Carboxyethylsilanetriol-Coated Magnetic Nanoparticles as an Ultrasensitive Immunoplatform for Electrochemical Magnetosensing of Cotinine

“…The charge transfer resistance ( R ct ) is represented by the semicircle diameter in the impedance spectrum. R ct reflects the kinetic electron transfer events occurring at the electrode interface of the redox probe. − Inset of Figure A shows the applied Randles equivalent circuit that analyzes the obtained EIS signal at each step. In this circuit, R s , W , and CPE are the ferri-ferro electrolyte resistance, Warburg impedance caused by ion diffusion, and constant phase element, respectively. , After each modification step, R ct was calculated to follow the electron transport process on the electrode surface.…”