Ultrafine Pd Nanoparticles Encapsulated in Mesoporous TiO₂ Region Selectively Confined in Bamboo Microchannels: An Ultrastable Continuous‐Flow Catalytic Hydrogenation Microreactor

Abstract

Plant‐based flow microreactors with natural channel structures, renewable properties, and environmental friendliness have increasingly gained popularity in heterogeneous catalysis. However, firmly immobilizing the catalysts simultaneously with ease and adaptability, maintaining great effectivity and long‐term stability, is still a fundamental challenge. Herein, a highly efficient and ultrastable bamboo‐based catalytic microreactor (CMR) containing mesoporous TiO2 (M‐TiO2)‐encapsulating ultrafine Pd nanoparticles (NPs) is constructed for the continuous‐flow hydrogenation of nitroaromatics. The fabrication of the Pd‐TiO2 catalysts in required bamboo microchannels (Pd‐TiO2/B CMR) mainly involves a two‐step region‐selective synthetic strategy with ultra‐low chemical usage, fast preparation, and low catalyst loading (0.007 wt%). The M‐TiO2 films: 1) provide abundant oxygen vacancies and enough open cavities to facilitate the growth of Pd NPs; 2) improve Pd dispersion and reduce particle size; 3) allow diffusion of reactants, and 4) induce strong metal‐support interactions for enhanced catalytic activity and stability. The optimized Pd‐TiO2/B CMR demonstrates high efficiency (>97%) and excellent stability (1,000 h) for the continuous‐flow hydrogenation of nitroaniline, even under intermittent operation (12 h on/12 h off for five cycles) or in a real aqueous matrix (>200 h), making it a promising candidate for Pd‐catalyzed hydrogenation.

Sustainable Synthesis of Ruthenium–Palladium-Based Nanonet Assembly for Efficient Reduction of 4-Nitrophenol and Nitrofurantoin

“…Furthermore, catalytic reduction can produce gentle and secure reaction conditions without the need for complicated systems, 28 significant quantities of organic additives, or additional requirements of light, electricity, or heat, and it can offer mild and more convenient reaction situations. 29,30 Nitrofurantoin (NFT) is a significant antibiotic medicine and most commonly used for urinary infections. 31 However, its excessive consumption can have harmful effects on human health, including organ toxicity, hearing loss, allergies, vomiting, nausea, arrhythmias, and acute pancreatitis.…”

“…The catalytic reduction is regarded as the most beneficial system because of the reasonably high activity, selectivity, and affordability. Furthermore, catalytic reduction can produce gentle and secure reaction conditions without the need for complicated systems, significant quantities of organic additives, or additional requirements of light, electricity, or heat, and it can offer mild and more convenient reaction situations. , …”