Ultrafine comminution-assisted ultrasonic-microwave synergistic extraction of Pueraria mirifica (Kudzu flower and root) flavonoids

Puerarin—A Promising Flavonoid: Biosynthesis, Extraction Methods, Analytical Techniques, and Biological Effects

“…Their research revealed that flavonoid extract yield was increased by increasing ultrasonic and microwave power. Microwave power, followed by ultrasonic time and power, were found to be the most effective combination factors for influencing the flavonoid extraction rate [51].…”

Puerariae lobatae Radix: Progress in Extraction, Separation Methods and Pharmacological Activities Research

“…In this study, the total content of flavonoids in kudzu root dregs was 8%, and the final extraction obtained by using UAE was 7.33%, with an extraction rate of 91.6%. Zhu et al [57] used an orthogonal test to investigate the effects of ultrasound power and extraction time on the flavonoids extract of kudzu root, and with the increase in ultrasound power, the flavonoids extraction rate showed a line increasing and then decreasing trend, and when the ultrasound power was in the range of 200-600 W, the two variables had a positive effect on the extraction rate. There was a positive correlation between the two variables, and the extraction rate reached the highest at 600 W. Thus, 600W was the optimal ultrasonic power for kudzu root flavonoids extraction.…”

“…Zhou et al [63] studied the process conditions of MAE of the total flavonoids of kudzu root by an orthogonal test, and the results showed that with 90% ethanol, the particle size of kudzu root for 40 mesh, a solidliquid ratio of 1:15, microwave power of 700 W, a temperature of 78 • C, pre-soaking for 1-2 h, and microwave radiation for 40 s, the leaching rate of the total flavonoids of kudzu root reached more than 96%, which is not only a high yield but also fast and energy-saving compared with the traditional hot leaching method. Zhu et al [57] investigated the effect of different microwave power on the extraction rate of kudzu root flavonoid compounds under 200 W, 400 W, 600 W, 800 W, and 1000 W microwave power conditions by combining MAE with UAE. The experimental results showed that with the increase of microwave power, the extraction rate of flavonoids showed a trend of increasing and then decreasing, and the extraction rate reached the maximum of 4.92% at the microwave power of 800 W (temperature of 55 • C, ultrasonic power of 400 W, 60% ethanol, solid-liquid ratio of 1:20, extraction time for 40 min).…”