Ultrafast synthesis of highly luminescent green- to near infrared-emitting CdTe nanocrystals in aqueous phase

Zou, Lei; Gu, Zhenyu; Zhang, Nan; Zhang, Yuliang; Fang, Zheng; Zhu, Weihong; Zhong, Xinhua

doi:10.1039/b801418c

Cited by 197 publications

(133 citation statements)

References 60 publications

(54 reference statements)

Supporting

Mentioning

127

Contrasting

Unclassified

Order By: Relevance

“…Moreover, Cd precursors which are improved by high pH and Te precursor stability support this fast growth process. 22 In regards to the effect of ligand-to-Cd ratio on the growth rate of NCs, the ligand-to-Cd molar ratios lower than 2 : 1 create an environment dominant with monothiol complexes rather than dithiol complexes. Under high pH conditions (>11), these monothiol complexes have greater solubility which improves the release of Cd and therefore support formation of CdTe monomers for nucleation and particle growth.…”

Section: Production and Optical Analysis Of Ncsmentioning

confidence: 99%

“…Thus, a fast growth rate is achieved by means of accelerated Cd release for crystal growth under low ligand-to-Cd molar rations and high pH conditions. 22 Once the Te source is depleted, the remaining Cd-monothiol complexes give a Cd rich surface which supports CdS shell formation around those very small CdTe particles resulting in core (small) /shell (thick) CdTe/CdS nanocrystals. This mechanism explains the high quality optical characteristics obtained by one-pot formation of core/shell (CS) structures.…”

Section: Production and Optical Analysis Of Ncsmentioning

confidence: 99%

See 1 more Smart Citation

One-pot aqueous synthesis of highly strained CdTe/CdS/ZnS nanocrystals and their interactions with cells

et al. 2015

View full text Add to dashboard Cite

In this work, a very simple one-pot synthetic approach was developed to generate aqueous CdTe/CdS/ZnS type-II/type-I red-emitting nanocrystals (NCs). Strain-induced optical properties of CdTe/CdS particles having core (small) /shell (thick) structure with a maximum quantum yield (QY max ) $ 57% were further improved with the overgrowth of a ZnS shell, resulting in a core (small) /shell (thick) /shell (small) structure (QY max $ 64%). The spectral properties were tuned further to the near-infrared region as the ZnS shell grew in thickness. X-ray powder diffraction (XRD) analysis and high-resolution transmission electron microscope (HRTEM) images showed the crystalline structure of NCs proving the epitaxial growth of ZnS without crystalline defects. Under continuous UV-irradiation for 5 h, the NCs did not exhibit any photodegradation but instead displayed a photo-annealing process. These extremely photostable NCs were further characterized in terms of their cytotoxicity and their cell labeling performances. The presence of a ZnS shell was found to reduce the toxicity of the CdTe/CdS NCs. Furthermore, aptamer-conjugated NCs were successfully utilized in targeted cell imaging. Promisingly, the aptamer-NCs bioconjugates were internalized by A549 cells within 2 hours of incubation and retained their fluorescence even after 24 hours of internalization.

show abstract

Section: Production and Optical Analysis Of Ncsmentioning

confidence: 99%

Section: Production and Optical Analysis Of Ncsmentioning

confidence: 99%

One-pot aqueous synthesis of highly strained CdTe/CdS/ZnS nanocrystals and their interactions with cells

et al. 2015

View full text Add to dashboard Cite

show abstract

“…23,26 QDs-3 was prepared by coprecipitation approach in aqueous phase with MPA capped. 9 These three types of QDs have core/shell structures, namely inorganic semiconductor crystalline substances as the core with comparable sizes, and organic layers as the shell with varying sizes. It is worth noting that the shell of QDs-1 is a macromolecule (poly [maleic anhydride-alt-1-octadecene], PMAO), while the shells of QDs-2 and QDs-3 are both small chemical compounds (GSH and MPA, respectively).…”

Section: Resultsmentioning

confidence: 99%

“…9 The basic properties of QDs including particle sizes, surface groups, and the atoms contained are provided in Table 1. The concentrations of QDs for toxicity assessment were determined with Cd 2+ content measured by inductively coupled plasma mass spectrometry (ICP-MS).…”

Section: Materials and Methods Materialsmentioning

confidence: 99%

“…Two major QD synthetic methods have been developed, namely the direct synthesis of QDs in the aqueous phase 9,10 and the thermal decomposition of precursors at high temperature. 11,12 The former method is quite simple and the resulting QDs are often capped by small molecules with thiol groups, while the latter method requires more complicated processing but has better optical properties, size distribution, and morphology.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Parallel comparative studies on toxicity of quantum dots synthesized and surface engineered with different methods in vitro and in vivo

Liu¹,

Ye²,

Wang³

et al. 2017

IJN

View full text Add to dashboard Cite

Quantum dots (QDs) have been considered to be promising probes for biosensing, bioimaging, and diagnosis. However, their toxicity issues caused by heavy metals in QDs remain to be addressed, in particular for their in vivo biomedical applications. In this study, a parallel comparative investigation in vitro and in vivo is presented to disclose the impact of synthetic methods and their following surface modifications on the toxicity of QDs. Cellular assays after exposure to QDs were conducted including cell viability assessment, DNA breakage study in a single cellular level, intracellular reactive oxygen species (ROS) receptor measurement, and transmission electron microscopy to evaluate their toxicity in vitro. Mice experiments after QD administration, including analysis of hemobiological indices, pharmacokinetics, histological examination, and body weight, were further carried out to evaluate their systematic toxicity in vivo. Results show that QDs fabricated by the thermal decomposition approach in organic phase and encapsulated by an amphiphilic polymer (denoted as QDs-1) present the least toxicity in acute damage, compared with those of QDs surface engineered by glutathione-mediated ligand exchange (denoted as QDs-2), and the ones prepared by coprecipitation approach in aqueous phase with mercaptopropionic acid capped (denoted as QDs-3). With the extension of the investigation time of mice respectively injected with QDs, we found that the damage caused by QDs to the organs can be gradually recovered. This parallel comparative investigation suggests that synthetic methods and their resulting surface microenvironment play vital roles in the acute toxicity profiles of QDs. The present study provides updated insights into the fabrication and surface engineering of QDs for their translational applications in theranostics.

show abstract

Glyconanoparticles: New Nanomaterials for Biological Applications

Garcı́a¹,

Gallo²,

Marradi³

et al. 2010

Engineered Carbohydrate‐Based Materials for Biomedical Applications

View full text Add to dashboard Cite

Ultrafast synthesis of highly luminescent green- to near infrared-emitting CdTe nanocrystals in aqueous phase

Cited by 197 publications

References 60 publications

One-pot aqueous synthesis of highly strained CdTe/CdS/ZnS nanocrystals and their interactions with cells

One-pot aqueous synthesis of highly strained CdTe/CdS/ZnS nanocrystals and their interactions with cells

Parallel comparative studies on toxicity of quantum dots synthesized and surface engineered with different methods in vitro and in vivo

Glyconanoparticles: New Nanomaterials for Biological Applications

Contact Info

Product

Resources

About