Ultrafast Screening and Quantitation of Pesticides in Food and Environmental Matrices by Solid-Phase Microextraction–Transmission Mode (SPME-TM) and Direct Analysis in Real Time (DART)

Gómez‐Ríos, Germán Augusto; Gionfriddo, Emanuela; Poole, Justen J.; Pawliszyn, Janusz

doi:10.1021/acs.analchem.7b01553

Cited by 112 publications

(88 citation statements)

References 81 publications

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“…In comparison with other AIMS methods, DART has the benefit of not requiring the addition of solvent post‐extraction in order to desorb samples, thus eliminating the need for extraneous input. SPME‐TM DART has already demonstrated its ability to handle time efficiently, but analyses had yet to be carried out on a one‐by‐one basis . In addition, the use of a 96‐SPME format is not a novel concept.…”

Section: Resultsmentioning

confidence: 99%

“…Thus far, SPME‐TM publications have focused on using rapid agitation of each mesh on a vortex (i.e. 3000 rpm) . This approach has worked well due to the high surface area of the mesh, which allows for adequate pre‐concentration in a short period of time.…”

Section: Resultsmentioning

confidence: 99%

“…TM device with a defined geometry and coated area) are one of the crucial components for guaranteeing reproducible quantitative results. Several articles published by the groups of Pawliszyn and Sacks have documented how coupling SPME‐TM to DART‐MS can provide analysts with reasonable quantitative results.…”

Section: Resultsmentioning

confidence: 99%

“…In 2014, Gómez‐Ríos et al optimized the TM format for SPME, which allowed analytes to be efficiently preconcentrated and quantified at low ppb levels . Since then, SPME‐TM has been employed to detect pesticides in water, consumer beverages, and milk, and it has also been coupled to a portable mass spectrometer for detecting drugs of abuse in oral fluid and urine, as well as being used in the form of polyether ether ketone as an alternate substrate . Sacks group at University of Cornell has also explored its application towards determination of volatiles from wine samples …”

Section: Introductionmentioning

confidence: 99%

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High‐throughput quantification of drugs of abuse in biofluids via 96‐solid‐phase microextraction–transmission mode and direct analysis in real time mass spectrometry

Vasiljević

Gómez‐Ríos

Li³

et al. 2019

Rapid Comm Mass Spectrometry

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Rationale The workload of clinical laboratories has been steadily increasing over the last few years. High‐throughput (HT) sample processing allows scientists to spend more time undertaking matters of critical thinking rather than laborious sample processing. Herein we introduce a HT 96‐solid‐phase microextraction (SPME) transmission mode (TM) system coupled to direct analysis in real time (DART) mass spectrometry (MS). Methods Model compounds (opioids) were extracted from urine and plasma samples using a 96‐SPME‐TM device. A standard voltage and pressure (SVP) DART source was used for all experiments. Examination of SPME‐TM performance was done using high‐resolution mass spectrometry (HRMS) in full scan mode (100–500 m/z), whereas quantitation of opioids was performed using triple quadrupole MS in multiple reaction monitoring mode and by using a matrix‐matched internal standard correction method. Results Thirteen points (0.5 to 200 ng mL−1) were used to establish a calibration curve. Low limits of quantitation (LOQ) were obtained (0.5 to 25 ng mL−1) for matrices used. Acceptable accuracy (71.4–129.4%) and repeatability (1.1–24%) were obtained for validation levels tested (0.5, 30 and 90 ng mL−1). In less than 1.5 hours, 96 samples were extracted, desorbed and processed using the 96‐SPME‐TM system coupled to DART‐MS. Conclusions A rapid HT method for detection of opioids in urine and plasma samples was developed. This study demonstrated that ambient ionization mass spectrometry coupled to robust sample preparation methods such as SPME‐TM can rapidly and efficiently screen/quantify target analytes in a HT context.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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High‐throughput quantification of drugs of abuse in biofluids via 96‐solid‐phase microextraction–transmission mode and direct analysis in real time mass spectrometry

Vasiljević

Gómez‐Ríos

Li³

et al. 2019

Rapid Comm Mass Spectrometry

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“…The headspace solid‐phase microextraction (HS‐SPME) sampling followed by GC coupled with MS analysis (HS‐SPME‐GC/MS) can be used as a method for investigating emission profiles. Historically, the use of SPME in chemical analysis was confined to HS sampling, but currently, SPME is used for different analytical tasks. By implementing the HS‐SPME technique, researchers can perform reliable analysis of VOCs of different kind of samples, such as foodstuffs, plants and their metabolites .…”

Section: Introductionmentioning

confidence: 99%

Volatile compounds in different parts of the fruit Psidium guajava L. cv. “Media China” identified at distinct phenological stages using HS‐SPME‐GC‐QTOF/MS

Elizalde-González

Segura-Rivera

2018

Phytochemical Analysis

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The most abundant VOC released by the immature fruit in the plantation overnight was (S)-limonene, and it concentrated in the outer skin (pericarp). The esters ethyl benzoate, ethyl octanoate, butyl-2-methylbutanoate, ethyl hexanoate, cis-3-hexenyl acetate, and ethyl butanoate were emitted by ripe whole fruits. During ripening ethyl benzoate reached a maximum production after three to five days, while the formation of the aldehydes benzaldehyde, hexanal and trans-2-hexen-1-al started thereafter.

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Trends in Multiresidue Analysis

Hernández‐Mesa

Lara

Moreno‐González

et al. 2020

Encyclopedia of Analytical Chemistry

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The global concern about food safety and environment quality has produced the development of a legal framework to control residues of organic compounds (e.g. pesticides and veterinary and human drugs). In this context, the establishment of analytical methods achieving satisfactory performances in terms of sensitivity, selectivity, resolution, identification, sample throughput, and applicability, is mandatory. Multiresidue methods mainly based on chromatographic techniques [i.e., gas chromatography (GC) and liquid chromatography (LC)] coupled to mass spectrometry (MS) are currently applied in routine laboratories. Furthermore, capillary electrophoresis (CE) has emerged as an alternative to LC and GC, owing to the development of on‐line preconcentration strategies for sensitivity enhancement. The recent integration of ion mobility spectrometry (IMS) in LC‐MS workflows also involves new possibilities for the separation of isomeric and isobaric residues, as well as for the separation of analytes of interest from background noise. New trends in multiresidue analysis point towards ambient ionization mass spectrometry (AIMS) strategies, which avoid chromatographic separations and substantially reduce analysis time. On the other hand, sample preparation has evolved through the development of miniaturized and environmentally friendly procedures according to the Green Chemistry principles. In addition, generic extraction procedures for multiclass analysis have been optimized, increasing sample throughput. This article aims to show an overview of the current trends in the analysis of pesticide and drugs in food and environmental samples, discussing the relevant advances in sample treatments and the technological evolution of the instrumental techniques. We hope to offer with this article a critical review of the analytical possibilities for routine analysis laboratories focused on monitoring of residues.

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Ultrafast Screening and Quantitation of Pesticides in Food and Environmental Matrices by Solid-Phase Microextraction–Transmission Mode (SPME-TM) and Direct Analysis in Real Time (DART)

Cited by 112 publications

References 81 publications

High‐throughput quantification of drugs of abuse in biofluids via 96‐solid‐phase microextraction–transmission mode and direct analysis in real time mass spectrometry

High‐throughput quantification of drugs of abuse in biofluids via 96‐solid‐phase microextraction–transmission mode and direct analysis in real time mass spectrometry

Volatile compounds in different parts of the fruit Psidium guajava L. cv. “Media China” identified at distinct phenological stages using HS‐SPME‐GC‐QTOF/MS

Trends in Multiresidue Analysis

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