Ultrafast microchannel plate photomultipliers

Kume, Hidehiro; Koyama, Kazuhiko; Nakatsugawa, Keiji; Suzuki, Seiji; Fatlowitz, David

doi:10.1364/ao.27.001170

Cited by 110 publications

(43 citation statements)

References 1 publication

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“…Another type is the microchannel plate (MCP) PMT in which standard dynodes are replaced by a multichannel plate [79]. An MCP is composed of a number of small glass capillaries with diameters ranging from ∼2 to 25 μm.…”

Section: Photodetectorsmentioning

confidence: 99%

Instrumentation for Time-of-Flight Positron Emission Tomography

Ullah

Pratiwi

Cheon

et al. 2016

Nucl Med Mol Imaging

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Positron emission tomography (PET) is a molecular imaging modality that provides information at the molecular level. This system is composed of radiation detectors to detect incoming coincident annihilation gamma photons emitted from the radiopharmaceutical injected into a patient's body and uses these data to reconstruct images. A major trend in PET instrumentation is the development of time-of-flight positron emission tomography (ToF-PET). In ToF-PET, the time information (the instant the radiation is detected) is incorporated for image reconstruction. Therefore, precise and accurate timing recording is crucial in ToF-PET. ToF-PET leads to better localization of the annihilation event and thus results in overall improvement in the signal-to-noise ratio (SNR) of the reconstructed image. Several factors affect the timing performance of ToF-PET. In this article, the background, early research and recent advances in ToF-PET instrumentation are presented. Emphasis is placed on the various types of scintillators, photodetectors and electronic circuitry for use in ToF-PET, and their impact on timing resolution is discussed.

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Section: Photodetectorsmentioning

confidence: 99%

Instrumentation for Time-of-Flight Positron Emission Tomography

Ullah

Pratiwi

Cheon

et al. 2016

Nucl Med Mol Imaging

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“…The latter solution can be implemented by using Micro Channel Plate (MCP) photomultipliers [9], which provide a very fast time response with high sensitivity and large active area.…”

Section: Derivation Of Design Guidelines For Particle Detectormentioning

confidence: 99%

Detection of fast flying nanoparticles by light scattering over a large volume

et al. 2015

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Detection of nanoparticles is of paramount importance for contamination control in ultra-clean systems. Light scattering is a well-known detection method which is applied in many different scientific and technology domains including atmospheric physics, environmental control, and biology. It allows contactless and remote detection of sub-micron size particles. However, methods for detecting a single fast moving particle smaller than 100 nm are lacking. In the present work we report a preliminary design study of an inline large area detector for nanoparticles larger than 50 nm which move with velocities up to 100 m/s. The detector design is based on light scattering using commercially available components. The presented design takes into account all challenges connected to the inline implementation of the scattering technique in the system: the need for the detector to have a large field of view to cover a volume with a footprint commensurate to an area of 100mm x 100mm, the necessity to sense nanoparticles transported at high velocity, and the requirement of large capture rate with a false detection as low as one false positive per week. The impact of all these stringent requirements on the expected sensitivity and performances of the device is analyzed by mean of a dedicated performance model.

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“…MCP's are characterized by a fast response time of a few tens of ps (129)(130)(131), which makes them useful intensifiers for detectors used in time-correlated spectroscopic applications. Coupled with a PSD, they form a powerful time-resolved position-sensitive detector as first demonstrated in ion detection experiments (132).…”

Section: The H33d Detectormentioning

confidence: 99%

Detectors for single-molecule fluorescence imaging and spectroscopy

Michalet

Siegmund

Vallerga

et al. 2007

Journal of Modern Optics

115

106

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Single-molecule observation, characterization and manipulation techniques have recently come to the forefront of several research domains spanning chemistry, biology and physics. Due to the exquisite sensitivity, specificity, and unmasking of ensemble averaging, single-molecule fluorescence imaging and spectroscopy have become, in a short period of time, important tools in cell biology, biochemistry and biophysics. These methods led to new ways of thinking about biological processes such as viral infection, receptor diffusion and oligomerization, cellular signaling, protein-protein or protein-nucleic acid interactions, and molecular machines. Such achievements require a combination of several factors to be met, among which detector sensitivity and bandwidth are crucial. We examine here the needed performance of photodetectors used in these types of experiments, the current state of the art for different categories of detectors, and actual and future developments of single-photon counting detectors for single-molecule imaging and spectroscopy.

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Ultrafast microchannel plate photomultipliers

Cited by 110 publications

References 1 publication

Instrumentation for Time-of-Flight Positron Emission Tomography

Instrumentation for Time-of-Flight Positron Emission Tomography

Detection of fast flying nanoparticles by light scattering over a large volume

Detectors for single-molecule fluorescence imaging and spectroscopy

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