Ultracytochemical Changes in the Distribution of Acid Phosphatase and Thiamine Pyrophosphatase Activity in the Nerve Cells of Vitamin E-Deficient Rats

Ultracytochemical Changes in the Distribution of Acid Phosphatase in the Liver Cells of Vitamin E Deficient and Vitamin E Supplemented Rats

“…In the neurons of vit. E deficient rats, however, ACPase decreased remarkably in the enlarged lysosomes (6). Present results suggest that ACPase may have been utilized in the process of lipid changes during peroxidation, or that the damage or rupture of lysosomal membranes in exposing lysosomes to lipid peroxidation may have caused its loss in the cytoplasm (43, 48).…”

“…2, 3, 4) and Kupffer cells (Figs. 5,6,7,8). A number of fat vacuoles ( Fig.1) and irregular tail-like forms of positive lysosomes were observed in predominantly the parenchymal cells (Figs.…”

“…Its biological function in the cellular metabolism is disputed (25,26,27,28). Recently, ultrastructural and ultracytochemical changes in the distribution of ACPase have been noted in nerve cells during vitamin E deficiency (6).…”